| ZAP-70: an essential kinase in T-cell signaling H Wang, TA Kadlecek, BB Au-Yeung, HE Sjolin Goodfellow, LY Hsu, ... Cold Spring Harbor Perspect Biol 1, a002980, 2010 | 457 | 2010 |
| A Ras-induced conformational switch in the Ras activator Son of sevenless TS Freedman, H Sondermann, GD Friedland, T Kortemme, D Bar-Sagi, ... Proc Natl Acad Sci USA 103 (45), 16692-16697, 2006 | 175 | 2006 |
| STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development A Limnander, P Depeille, TS Freedman, J Liou, M Leitges, T Kurosaki, ... Nat Immunol 12 (5), 425, 2011 | 136 | 2011 |
| Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling YX Tan, BN Manz, TS Freedman, C Zhang, KM Shokat, A Weiss Nat Immunol 15 (2), 186-194, 2014 | 108 | 2014 |
| Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex SL Kazmirski, M Podobnik, TF Weitze, M O'Donnell, J Kuriyan Proc Natl Acad Sci U S A 101 (48), 16750-5, 2004 | 71 | 2004 |
| Nucleotide-induced conformational changes in an isolated Escherichia coli DNA polymerase III clamp loader subunit M Podobnik, TF Weitze, M O'Donnell, J Kuriyan Structure 11 (3), 253-63, 2003 | 41 | 2003 |
| The Src-family kinase Lyn in immunoreceptor signaling BF Brian IV, TS Freedman Endocrinology, 2021 | 40 | 2021 |
| Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1 TS Freedman, H Sondermann, O Kuchment, GD Friedland, T Kortemme, ... Structure 17 (1), 41-53, 2009 | 38 | 2009 |
| LynA regulates an inflammation-sensitive signaling checkpoint in macrophages TS Freedman, YX Tan, KM Skrzypczynska, BN Manz, FV Sjaastad, ... eLife 4, e09183, 2015 | 36 | 2015 |
| Lessons of COVID-19: A roadmap for post-pandemic science TS Freedman, MB Headley, N Serwas, M Ruhland, CA Castellanos, ... J Exp Med 217 (9), e20201276, 2020 | 15 | 2020 |
| Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells BF Brian IV, AS Jolicoeur, CR Guerrero, MG Nunez, ZE Sychev, SA Hegre, ... eLife 8, e46043, 2019 | 13 | 2019 |
| Regulation of myeloid-cell activation JT Greene, BF Brian IV, SE Senevirathne, TS Freedman Curr Opin Immunol 73, 34-42, 2021 | 11 | 2021 |
| Immunopharmacology and quantitative analysis of tyrosine kinase signaling BF Brian IV, CR Guerrero, TS Freedman Curr Protoc Immunol 130, e104, 2020 | 8 | 2020 |
| A dominant function of LynB kinase in preventing autoimmunity BF Brian IV, ML Sauer, JT Greene, SE Senevirathne, AJ Lindstedt, ... Sci Adv 8, eabj5227, 2022 | 7* | 2022 |
| SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 binding BF Brian IV, FV Sjaastad, TS Freedman Sci Rep 12, 5875, 2022 | 6 | 2022 |
| Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors DM Rasmussen, MM Semonis, JT Greene, JM Muretta, AR Thompson, ... bioRxiv, 2023 | 1 | 2023 |
| ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer SY Bae, HE Bergom, A Day, JT Greene, TS Freedman, J Hwang, ... Front Endocrinol 14, 403, 2023 | 1 | 2023 |
| (Abstract) Lyn kinase regulates myeloid-cell responses to mammary tumors JT Greene, BF Brian IV, A Bapat, TS Freedman Cancer Immunology Research 11 (12_Supplement), PR02-PR02, 2023 | | 2023 |
| Primary infection with Zika virus provides one-way heterologous protection against Spondweni virus infection in rhesus macaques AS Jaeger, CM Crooks, AM Weiler, MI Bliss, S Rybarczyk, A Richardson, ... Science Advances 9 (26), eadg3444, 2023 | | 2023 |
| (Abstract) ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer (B057) SY Bae, HE Bergom, A Day, JT Greene, TS Freedman, JH Hwang, ... Cancer Research 83 (11 Supplement), B057-B057, 2023 | | 2023 |
Ben Frank Brian IVPostdoctoral scholarVerified email at berkeley.edu
