| Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations SB Hansen, G Sulzenbacher, T Huxford, P Marchot, P Taylor, Y Bourne The EMBO journal 24 (20), 3635-3646, 2005 | 762 | 2005 |
| Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2 SB Hansen, X Tao, R MacKinnon Nature 477 (7365), 495-498, 2011 | 645 | 2011 |
| Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α‐neurotoxins and nicotinic receptors Y Bourne, TT Talley, SB Hansen, P Taylor, P Marchot The EMBO journal 24 (8), 1512-1522, 2005 | 382 | 2005 |
| Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel C Bouzat, F Gumilar, G Spitzmaul, HL Wang, D Rayes, SB Hansen, ... Nature 430 (7002), 896-900, 2004 | 334 | 2004 |
| Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol H Wang, JA Kulas, C Wang, DM Holtzman, HA Ferris, SB Hansen Proceedings of the National Academy of Sciences 118 (33), e2102191118, 2021 | 201 | 2021 |
| Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica SB Hansen, TT Talley, Z Radic, P Taylor Journal of Biological Chemistry 279 (23), 24197-24202, 2004 | 191 | 2004 |
| Studies on the mechanism of general anesthesia MA Pavel, EN Petersen, H Wang, RA Lerner, SB Hansen Proceedings of the National Academy of Sciences 117 (24), 13757-13766, 2020 | 183 | 2020 |
| Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence F Gao, N Bren, TP Burghardt, S Hansen, RH Henchman, P Taylor, ... Journal of Biological Chemistry 280 (9), 8443-8451, 2005 | 177 | 2005 |
| Methods for searching private social network data AS Hansen, SB Hansen US Patent 8,121,999, 2012 | 160 | 2012 |
| The role of high cholesterol in SARS-CoV-2 infectivity. H Wang, Z Yuan, MA Pavel, SM Jablonski, J Jablonski, R Hobson, ... Journal of Biological Chemistry, 104763, 2023 | 153* | 2023 |
| Lipid agonism: The PIP2 paradigm of ligand-gated ion channels SB Hansen Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 149 | 2015 |
| Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-α-subunit interfaces of heteromeric neuronal nicotinic receptors SB Hansen, P Taylor Journal of molecular biology 369 (4), 895-901, 2007 | 146 | 2007 |
| Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein SB Hansen, Z Radić, TT Talley, BE Molles, T Deerinck, I Tsigelny, ... Journal of Biological Chemistry 277 (44), 41299-41302, 2002 | 129 | 2002 |
| Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D EN Petersen, HW Chung, A Nayebosadri, SB Hansen Nature communications 7 (1), 13873, 2016 | 101 | 2016 |
| Tools for understanding nanoscale lipid regulation of ion channels CV Robinson, T Rohacs, SB Hansen Trends in biochemical sciences 44 (9), 795-806, 2019 | 75 | 2019 |
| An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance SB Hansen, HL Wang, P Taylor, SM Sine Journal of Biological Chemistry 283 (52), 36066-36070, 2008 | 69 | 2008 |
| A soluble fluorescent binding assay reveals PIP2 antagonism of TREK-1 channels C Cabanos, M Wang, X Han, SB Hansen Cell reports 20 (6), 1287-1294, 2017 | 68 | 2017 |
| Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes P Taylor, TT Talley, SB Hansen, RE Hibbs, J Shi Biochemical pharmacology 74 (8), 1164-1171, 2007 | 61 | 2007 |
| Curariform antagonists bind in different orientations to acetylcholine-binding protein F Gao, N Bern, A Little, HL Wang, SB Hansen, TT Talley, P Taylor, ... Journal of Biological Chemistry 278 (25), 23020-23026, 2003 | 56 | 2003 |
| Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop F Gao, G Mer, M Tonelli, SB Hansen, TP Burghardt, P Taylor, SM Sine Molecular pharmacology 70 (4), 1230-1235, 2006 | 47 | 2006 |
Hao WangMIT, Scripps ResearchVerified email at mit.edu
