Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity PA Lang, KS Lang, HC Xu, M Grusdat, IA Parish, M Recher, AR Elford, ... Proceedings of the National Academy of Sciences 109 (4), 1210-1215, 2012 | 367 | 2012 |
Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus N Honke, N Shaabani, G Cadeddu, UR Sorg, DE Zhang, M Trilling, ... Nature immunology 13 (1), 51-57, 2012 | 251 | 2012 |
Multiple functions of USP18 N Honke, N Shaabani, DE Zhang, C Hardt, KS Lang Cell death & disease 7 (11), e2444-e2444, 2016 | 138 | 2016 |
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ... Science translational medicine 14 (637), eabi9215, 2022 | 131 | 2022 |
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions MA Bakowski, N Beutler, KC Wolff, MG Kirkpatrick, E Chen, TTH Nguyen, ... Nature communications 12 (1), 3309, 2021 | 96 | 2021 |
Involvement of Toso in activation of monocytes, macrophages, and granulocytes KS Lang, PA Lang, A Meryk, AA Pandyra, LM Boucher, VI Pozdeev, ... Proceedings of the National Academy of Sciences 110 (7), 2593-2598, 2013 | 80 | 2013 |
Usp18 Driven Enforced Viral Replication in Dendritic Cells Contributes to Break of Immunological Tolerance in Autoimmune Diabetes N Honke, N Shaabani, DE Zhang, G Iliakis, HC Xu, D Häussinger, ... PLoS pathogens 9 (10), e1003650, 2013 | 65 | 2013 |
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production V Khairnar, V Duhan, SK Maney, N Honke, N Shaabani, AA Pandyra, ... Nature communications 6 (1), 6217, 2015 | 59 | 2015 |
Oxidized ATP inhibits T‐cell‐mediated autoimmunity PA Lang, D Merkler, P Funkner, N Shaabani, A Meryk, C Krings, ... European journal of immunology 40 (9), 2401-2408, 2010 | 55 | 2010 |
IL-27 promotes the expansion of self-renewing CD8+ T cells in persistent viral infection Z Huang, J Zak, I Pratumchai, N Shaabani, VF Vartabedian, N Nguyen, ... Journal of Experimental Medicine 216 (8), 1791-1808, 2019 | 53 | 2019 |
Reactive oxygen species delay control of lymphocytic choriomeningitis virus PA Lang, HC Xu, M Grusdat, DR McIlwain, AA Pandyra, IS Harris, ... Cell Death & Differentiation 20 (4), 649-658, 2013 | 50 | 2013 |
CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection N Shaabani, V Duhan, V Khairnar, A Gassa, R Ferrer-Tur, D Häussinger, ... Cell death & disease 7 (11), e2446-e2446, 2016 | 49 | 2016 |
Evaluation of SARS-CoV-2 main protease inhibitors using a novel cell-based assay W Cao, CCD Cho, ZZ Geng, N Shaabani, XR Ma, EC Vatansever, ... ACS central science 8 (2), 192-204, 2022 | 35 | 2022 |
A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ... | 34 | 2021 |
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ... European Journal of Medicinal Chemistry 240, 114570, 2022 | 31 | 2022 |
Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency PA Lang, N Shaabani, S Borkens, N Honke, S Scheu, S Booth, D Brenner, ... Journal of allergy and clinical immunology 131 (3), 815-824. e2, 2013 | 31 | 2013 |
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ... European Journal of Medicinal Chemistry 240, 114596, 2022 | 26 | 2022 |
Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2 X Zhou, F Ma, J Xie, M Yuan, Y Li, N Shaabani, F Zhao, D Huang, NC Wu, ... Cell reports 35 (6), 2021 | 25 | 2021 |
Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection PA Lang, A Meryk, AA Pandyra, D Brenner, A Brüstle, HC Xu, K Merches, ... Cell Death & Differentiation 22 (1), 164-173, 2015 | 24 | 2015 |
HYBRiD: hydrogel-reinforced DISCO for clearing mammalian bodies V Nudell, Y Wang, Z Pang, NK Lal, M Huang, N Shaabani, W Kanim, ... Nature methods 19 (4), 479-485, 2022 | 22 | 2022 |