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Thota Ganesh
Thota Ganesh
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Cited by
Year
Withaferin A inhibits breast cancer invasion and metastasis at sub‐cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
JT Thaiparambil, L Bender, T Ganesh, E Kline, P Patel, Y Liu, ...
International journal of cancer 129 (11), 2744-2755, 2011
2922011
Cyclooxygenase‐2 in epilepsy
A Rojas, J Jiang, T Ganesh, MS Yang, N Lelutiu, P Gueorguieva, ...
Epilepsia 55 (1), 17-25, 2014
1952014
Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation
J Jiang, Y Quan, T Ganesh, WA Pouliot, FE Dudek, R Dingledine
Proceedings of the National Academy of Sciences 110 (9), 3591-3596, 2013
1712013
The bioactive Taxol conformation on β-tubulin: Experimental evidence from highly active constrained analogs
T Ganesh, RC Guza, S Bane, R Ravindra, N Shanker, AS Lakdawala, ...
Proceedings of the National Academy of Sciences 101 (27), 10006-10011, 2004
1402004
Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases
Y Chang, T Ganesh, JR Horton, A Spannhoff, J Liu, A Sun, X Zhang, ...
Journal of molecular biology 400 (1), 1-7, 2010
1312010
Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2
J Jiang, T Ganesh, Y Du, Y Quan, G Serrano, M Qui, I Speigel, A Rojas, ...
Proceedings of the National Academy of Sciences 109 (8), 3149-3154, 2012
1262012
Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits
SME Smith, J Min, T Ganesh, B Diebold, T Kawahara, Y Zhu, J McCoy, ...
Chemistry & biology 19 (6), 752-763, 2012
1252012
Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus
J Jiang, M Yang, Y Quan, P Gueorguieva, T Ganesh, R Dingledine
Neurobiology of disease 76, 126-136, 2015
1052015
Modulating neuroinflammation and oxidative stress to prevent epilepsy and improve outcomes after traumatic brain injury
CL Eastman, R D'Ambrosio, T Ganesh
Neuropharmacology 172, 107907, 2020
942020
Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor
J Jiang, T Ganesh, Y Du, P Thepchatri, A Rojas, I Lewis, S Kurtkaya, L Li, ...
Proceedings of the National Academy of Sciences 107 (5), 2307-2312, 2010
942010
Asymmetric synthesis of the putative structure of (−)-oryzoxymycin
ME Bunnage, T Ganesh, IB Masesane, D Orton, PG Steel
Organic Letters 5 (3), 239-242, 2003
882003
Prostanoid receptor EP2 as a therapeutic target: Miniperspective
T Ganesh
Journal of medicinal chemistry 57 (11), 4454-4465, 2014
852014
Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3 ‘bridged paclitaxel analogues
T Ganesh, C Yang, A Norris, T Glass, S Bane, R Ravindra, A Banerjee, ...
Journal of medicinal chemistry 50 (4), 713-725, 2007
852007
Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus
A Rojas, T Ganesh, N Lelutiu, P Gueorguieva, R Dingledine
Neuropharmacology 93, 15-27, 2015
822015
Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects
H Yuan, SJ Myers, G Wells, KL Nicholson, SA Swanger, P Lyuboslavsky, ...
Neuron 85 (6), 1305-1318, 2015
812015
Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus-induced deficits in the novel object recognition task in rats
A Rojas, T Ganesh, Z Manji, T O'neill, R Dingledine
Neuropharmacology 110, 419-430, 2016
762016
High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases
J Zielonka, G Cheng, M Zielonka, T Ganesh, A Sun, J Joseph, R Michalski, ...
Journal of Biological Chemistry 289 (23), 16176-16189, 2014
752014
Improved biochemical strategies for targeted delivery of taxoids
T Ganesh
Bioorganic & medicinal chemistry 15 (11), 3597-3623, 2007
742007
Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells
E Curry, I Green, N Chapman-Rothe, E Shamsaei, S Kandil, FL Cherblanc, ...
Clinical epigenetics 7, 1-12, 2015
722015
Diels–alder approach to tetralin-based constrained α-amino acid derivatives
S Kotha, T Ganesh, AK Ghosh
Bioorganic & medicinal chemistry letters 10 (15), 1755-1757, 2000
642000
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