Follow
igor shats
igor shats
National Institute of Environmental Health Sciences
Verified email at nih.gov
Title
Cited by
Cited by
Year
Activated p53 suppresses the histone methyltransferase EZH2 gene
X Tang, M Milyavsky, I Shats, N Erez, N Goldfinger, V Rotter
Oncogene 23 (34), 5759-5769, 2004
2512004
Regulation of AIF expression by p53
P Stambolsky, L Weisz, I Shats, Y Klein, N Goldfinger, M Oren, V Rotter
Cell Death & Differentiation 13 (12), 2140-2149, 2006
2332006
p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner
A Molchadsky, I Shats, N Goldfinger, M Pevsner-Fischer, M Olson, ...
PloS one 3 (11), e3707, 2008
2162008
p53-dependent down-regulation of telomerase is mediated by p21waf1
I Shats, M Milyavsky, X Tang, P Stambolsky, N Erez, R Brosh, I Kogan, ...
Journal of Biological Chemistry 279 (49), 50976-50985, 2004
2012004
Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype
M Milyavsky, I Shats, N Erez, X Tang, S Senderovich, A Meerson, ...
Cancer research 63 (21), 7147-7157, 2003
1892003
Bacteria boost mammalian host NAD metabolism by engaging the deamidated biosynthesis pathway
I Shats, JG Williams, J Liu, MV Makarov, X Wu, FB Lih, LJ Deterding, ...
Cell metabolism 31 (3), 564-579. e7, 2020
1512020
Using a stem cell–based signature to guide therapeutic selection in cancer
I Shats, ML Gatza, JT Chang, S Mori, J Wang, J Rich, JR Nevins
Cancer research 71 (5), 1772-1780, 2011
1412011
Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1α activation and inhibits tumor growth
N Erez, M Milyavsky, R Eilam, I Shats, N Goldfinger, V Rotter
Cancer research 63 (24), 8777-8783, 2003
1282003
hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis
I Kogan, N Goldfinger, M Milyavsky, M Cohen, I Shats, G Dobler, ...
Cancer research 66 (7), 3531-3540, 2006
1272006
The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation
Y Tabach, M Milyavsky, I Shats, R Brosh, O Zuk, A Yitzhaky, R Mantovani, ...
Molecular systems biology 1 (1), 2005.0022, 2005
882005
Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect
M Milyavsky, I Shats, A Cholostoy, R Brosh, Y Buganim, L Weisz, I Kogan, ...
Cancer cell 11 (2), 133-146, 2007
842007
Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation
M Milyavsky, Y Tabach, I Shats, N Erez, Y Cohen, X Tang, M Kalis, ...
Cancer research 65 (11), 4530-4543, 2005
722005
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer
Q Xu, Y Li, X Gao, K Kang, JG Williams, L Tong, J Liu, M Ji, LJ Deterding, ...
Nature communications 11 (1), 3978, 2020
682020
Expression level is a key determinant of E2F1-mediated cell fate
I Shats, M Deng, A Davidovich, C Zhang, JS Kwon, D Manandhar, ...
Cell Death & Differentiation 24 (4), 626-637, 2017
502017
FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function
I Shats, ML Gatza, B Liu, SP Angus, L You, JR Nevins
Cancer research 73 (19), 6056-6067, 2013
502013
CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data
K Kang, Q Meng, I Shats, DM Umbach, M Li, Y Li, X Li, L Li
PLoS computational biology 15 (12), e1007510, 2019
482019
Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate–induced death by attenuating activating transcription factor 3 induction
Y Buganim, E Kalo, R Brosh, H Besserglick, I Nachmany, Y Rais, ...
Cancer research 66 (22), 10750-10759, 2006
442006
Activation of p53 protein by telomeric (TTAGGG) n repeats
M Milyavsky, A Mimran, S Senderovich, I Zurer, N Erez, I Shats, ...
Nucleic acids research 29 (24), 5207-5215, 2001
432001
Predicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines
Y Li, DM Umbach, JM Krahn, I Shats, X Li, L Li
BMC genomics 22, 1-18, 2021
362021
Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repression
B Liu, I Shats, SP Angus, ML Gatza, JR Nevins
Journal of Biological Chemistry 288 (34), 24581-24589, 2013
362013
The system can't perform the operation now. Try again later.
Articles 1–20