Structure-based decoupling of the pro-and anti-inflammatory functions of interleukin-10 RA Saxton, N Tsutsumi, LL Su, GC Abhiraman, K Mohan, LT Henneberg, ... Science 371 (6535), eabc8433, 2021 | 97 | 2021 |
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling N Tsutsumi, S Mukherjee, D Waghray, CY Janda, KM Jude, Y Miao, ... elife 9, e58464, 2020 | 80 | 2020 |
Structural basis of GABA reuptake inhibition Z Motiwala, NG Aduri, H Shaye, GW Han, JH Lam, V Katritch, V Cherezov, ... Nature 606 (7915), 820-826, 2022 | 47 | 2022 |
The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells BK Prabhala, NG Aduri, N Sharma, A Shaheen, A Sharma, M Iqbal, ... Journal of Biological Chemistry 293 (3), 1007-1017, 2018 | 25 | 2018 |
New insights into the substrate specificities of proton-coupled oligopeptide transporters from E. coli by a pH sensitive assay BK Prabhala, NG Aduri, JM Jensen, HA Ernst, N Iram, M Rahman, O Mirza FEBS letters 588 (4), 560-565, 2014 | 25 | 2014 |
Salt bridge swapping in the EXXERFXYY motif of proton-coupled oligopeptide transporters NG Aduri, BK Prabhala, HA Ernst, FS Jørgensen, L Olsen, O Mirza Journal of Biological Chemistry 290 (50), 29931-29940, 2015 | 23 | 2015 |
Molecular architecture of the Jumonji C family histone demethylase KDM5B J Dorosz, LH Kristensen, NG Aduri, O Mirza, R Lousen, S Bucciarelli, ... Scientific Reports 9 (1), 4019, 2019 | 21 | 2019 |
Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR BK Prabhala, NG Aduri, M Iqbal, M Rahman, M Gajhede, PR Hansen, ... Research in microbiology 168 (5), 443-449, 2017 | 18 | 2017 |
A structural view onto disease-linked mutations in the human neutral amino acid exchanger ASCT1 P Stehantsev, A Stetsenko, M Nemchinova, NG Aduri, SJ Marrink, C Gati, ... Computational and Structural Biotechnology Journal 19, 5246-5254, 2021 | 12 | 2021 |
Investigation of the Substrate Specificity of the Proton Coupled Peptide Transporter PepTSo from Shewanella oneidensis BK Prabhala, NG Aduri, H Hald, O Mirza International journal of peptide research and therapeutics 21, 1-6, 2015 | 10 | 2015 |
Peptide selectivity of the proton-coupled oligopeptide transporter from Neisseria meningitidis N Sharma, NG Aduri, A Iqbal, BK Prabhala, O Mirza Journal of Molecular Microbiology and Biotechnology 26 (5), 312-319, 2016 | 9 | 2016 |
Critical role of a conserved transmembrane lysine in substrate recognition by the proton-coupled oligopeptide transporter YjdL JM Jensen, NG Aduri, BK Prabhala, R Jahnsen, H Franzyk, O Mirza The International Journal of Biochemistry & Cell Biology 55, 311-317, 2014 | 9 | 2014 |
Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state NG Aduri, HA Ernst, BK Prabhala, S Bhatt, T Boesen, M Gajhede, O Mirza Biochemical and Biophysical Research Communications 495 (2), 1738-1743, 2018 | 8 | 2018 |
Molecular dynamics simulations reveal the proton: peptide coupling mechanism in the bacterial proton-coupled oligopeptide transporter YbgH NG Aduri, M Montefiori, R Khalil, M Gajhede, FS Jørgensen, O Mirza ACS Omega 4 (1), 2040-2046, 2019 | 3 | 2019 |
Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1 M Rafiq, HA Ernst, NG Aduri, BK Prabhala, S Tufail, M Rahman, MB Bloch, ... Protein Expression and Purification 190, 105990, 2022 | 2 | 2022 |
Functional Characterization of the Putative POT from Clostridium perfringens H Gharabli, M Rafiq, A Iqbal, R Yan, NG Aduri, N Sharma, BK Prabhala, ... Biology 12 (5), 651, 2023 | | 2023 |