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Massimo Lopes
Massimo Lopes
Full Professor, Institute of Molecular Cancer Research, University of Zurich
Verified email at imcr.uzh.ch - Homepage
Title
Cited by
Cited by
Year
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
JM Sogo, M Lopes, M Foiani
Science 297 (5581), 599-602, 2002
9962002
The DNA replication checkpoint response stabilizes stalled replication forks
M Lopes, C Cotta-Ramusino, A Pellicioli, G Liberi, P Plevani, ...
Nature 412 (6846), 557-561, 2001
9132001
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
M Lopes, M Foiani, JM Sogo
Molecular cell 21 (1), 15-27, 2006
6772006
Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
R Zellweger, D Dalcher, K Mutreja, M Berti, JA Schmid, R Herrador, ...
Journal of Cell Biology 208 (5), 563-579, 2015
6402015
Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis
Y Hashimoto, A Ray Chaudhuri, M Lopes, V Costanzo
Nature structural & molecular biology 17 (11), 1305-1311, 2010
5682010
Topoisomerase I poisoning results in PARP-mediated replication fork reversal
A Ray Chaudhuri, Y Hashimoto, R Herrador, KJ Neelsen, D Fachinetti, ...
Nature structural & molecular biology 19 (4), 417-423, 2012
5032012
Replication fork reversal in eukaryotes: from dead end to dynamic response
KJ Neelsen, M Lopes
Nature reviews Molecular cell biology 16 (4), 207-220, 2015
4992015
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
M Berti, A Ray Chaudhuri, S Thangavel, S Gomathinayagam, S Kenig, ...
Nature structural & molecular biology 20 (3), 347-354, 2013
4502013
Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
A Pellicioli, C Lucca, G Liberi, F Marini, M Lopes, P Plevani, A Romano, ...
The EMBO journal, 1999
4491999
Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase
G Liberi, G Maffioletti, C Lucca, I Chiolo, A Baryshnikova, ...
Genes & development 19 (3), 339-350, 2005
3672005
DNA2 drives processing and restart of reversed replication forks in human cells
S Thangavel, M Berti, M Levikova, C Pinto, S Gomathinayagam, ...
Journal of Cell Biology 208 (5), 545-562, 2015
3542015
Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells
IM Toller, KJ Neelsen, M Steger, ML Hartung, MO Hottiger, M Stucki, ...
Proceedings of the National Academy of Sciences 108 (36), 14944-14949, 2011
3442011
Replication fork reversal triggers fork degradation in BRCA2-defective cells
S Mijic, R Zellweger, N Chappidi, M Berti, K Jacobs, K Mutreja, S Ursich, ...
Nature communications 8 (1), 859, 2017
3422017
Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells
C Cotta-Ramusino, D Fachinetti, C Lucca, Y Doksani, M Lopes, J Sogo, ...
Molecular cell 17 (1), 153-159, 2005
3112005
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ...
Nature cell biology 18 (7), 777-789, 2016
2782016
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality
E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ...
Cancer cell 33 (6), 1078-1093. e12, 2018
2582018
Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness
H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ...
Cell stem cell 21 (2), 225-240. e5, 2017
2522017
Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA
N Mojas, M Lopes, J Jiricny
Genes & development 21 (24), 3342-3355, 2007
2392007
Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity
M Vujanovic, J Krietsch, MC Raso, N Terraneo, R Zellweger, JA Schmid, ...
Molecular cell 67 (5), 882-890. e5, 2017
2332017
The plasticity of DNA replication forks in response to clinically relevant genotoxic stress
M Berti, D Cortez, M Lopes
Nature reviews Molecular cell biology 21 (10), 633-651, 2020
2242020
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