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Xiaopu Zhou
Xiaopu Zhou
The Centre for Applied Genomics, The Hospital for Sick Children
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline
AKY Fu, KW Hung, MYF Yuen, X Zhou, DSY Mak, ICW Chan, TH Cheung, ...
Proceedings of the National Academy of Sciences 113 (19), E2705-E2713, 2016
3352016
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
X Zhou, Y Chen, KY Mok, TCY Kwok, VCT Mok, Q Guo, FC Ip, Y Chen, ...
Nature communications 10 (1), 3310, 2019
1502019
Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and staging
Y Jiang, X Zhou, FC Ip, P Chan, Y Chen, NCH Lai, K Cheung, RMN Lo, ...
Alzheimer's & Dementia 18 (1), 88-102, 2022
822022
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
X Zhou, Y Chen, KY Mok, Q Zhao, K Chen, Y Chen, J Hardy, Y Li, AKY Fu, ...
Proceedings of the National Academy of Sciences 115 (8), 1697-1706, 2018
802018
Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice
Y Duan, T Ye, Z Qu, Y Chen, A Miranda, X Zhou, KC Lok, Y Chen, AKY Fu, ...
Nature Biomedical Engineering 6 (2), 168-180, 2022
422022
Cdk5 regulates activity-dependent gene expression and dendrite development
Z Liang, T Ye, X Zhou, KO Lai, AKY Fu, NY Ip
Journal of Neuroscience 35 (45), 15127-15134, 2015
392015
Underrepresented populations in Parkinson's genetics research: current landscape and future directions
AF Schumacher‐Schuh, A Bieger, O Okunoye, KY Mok, SY Lim, ...
Movement Disorders 37 (8), 1593-1604, 2022
382022
Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population
X Zhou, Y Chen, FCF Ip, NCH Lai, YYT Li, Y Jiang, H Zhong, Y Chen, ...
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 12 (1 …, 2020
292020
Axin regulates dendritic spine morphogenesis through Cdc42-dependent signaling
Y Chen, Z Liang, E Fei, Y Chen, X Zhou, W Fang, WY Fu, AKY Fu, NY Ip
PloS one 10 (7), e0133115, 2015
282015
Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
JJ Kim, D Vitale, DV Otani, MM Lian, K Heilbron, H Iwaki, J Lake, ...
Nature genetics 56 (1), 27-36, 2024
272024
Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study
M Rizig, S Bandres-Ciga, MB Makarious, OO Ojo, PW Crea, OV Abiodun, ...
The Lancet Neurology 22 (11), 1015-1025, 2023
272023
Polygenic score models for Alzheimer’s disease: from research to clinical applications
X Zhou, YYT Li, AKY Fu, NY Ip
Frontiers in Neuroscience 15, 650220, 2021
272021
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer’s disease
P Xu, JC Chang, X Zhou, W Wang, M Bamkole, E Wong, K Bettayeb, ...
Journal of Experimental Medicine 218 (8), e20202446, 2021
242021
APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease intervention
X Zhou, AKY Fu, NY Ip
Current Opinion in Neurobiology 69, 58-67, 2021
232021
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction
X Zhou, Y Chen, FCF Ip, Y Jiang, H Cao, G Lv, H Zhong, J Chen, T Ye, ...
Communications Medicine 3 (1), 49, 2023
19*2023
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's disease
Y Jiang, X Zhou, HY Wong, L Ouyang, FCF Ip, V Chau, SF Lau, W Wu, ...
Nature Aging, 2022
182022
Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer’s Disease
Y Chen, J Xu, X Zhou, S Liu, Y Zhang, S Ma, AKY Fu, NY Ip, Y Chen
ACS chemical neuroscience 10 (9), 3986-3996, 2019
152019
Multi‐Omics‐Based Autophagy‐Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology
JC Park, N Barahona‐Torres, SY Jang, KY Mok, HJ Kim, SH Han, KH Cho, ...
Advanced Science 9 (23), 2201212, 2022
122022
Association of SPI1 haplotypes with altered SPI1 gene expression and Alzheimer’s disease risk
H Cao, X Zhou, Y Chen, FCF Ip, Y Chen, NCH Lai, R Lo, EPS Tong, ...
Journal of Alzheimer's Disease 86 (4), 1861-1873, 2022
102022
Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)
C Towns, M Richer, S Jasaityte, EJ Stafford, J Joubert, T Antar, ...
npj Parkinson's Disease 9 (1), 131, 2023
82023
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