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Xiaopu Zhou
Xiaopu Zhou
The Centre for Applied Genomics, The Hospital for Sick Children
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline
AKY Fu, KW Hung, MYF Yuen, X Zhou, DSY Mak, ICW Chan, TH Cheung, ...
Proceedings of the National Academy of Sciences 113 (19), E2705-E2713, 2016
3212016
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
X Zhou, Y Chen, KY Mok, TCY Kwok, VCT Mok, Q Guo, FC Ip, Y Chen, ...
Nature communications 10 (1), 3310, 2019
1352019
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis
X Zhou, Y Chen, KY Mok, Q Zhao, K Chen, Y Chen, J Hardy, Y Li, AKY Fu, ...
Proceedings of the National Academy of Sciences 115 (8), 1697-1706, 2018
772018
Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and staging
Y Jiang, X Zhou, FC Ip, P Chan, Y Chen, NCH Lai, K Cheung, RMN Lo, ...
Alzheimer's & Dementia 18 (1), 88-102, 2022
742022
Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice
Y Duan, T Ye, Z Qu, Y Chen, A Miranda, X Zhou, KC Lok, Y Chen, AKY Fu, ...
Nature Biomedical Engineering 6 (2), 168-180, 2022
372022
Cdk5 regulates activity-dependent gene expression and dendrite development
Z Liang, T Ye, X Zhou, KO Lai, AKY Fu, NY Ip
Journal of Neuroscience 35 (45), 15127-15134, 2015
372015
Underrepresented populations in Parkinson's genetics research: current landscape and future directions
AF Schumacher‐Schuh, A Bieger, O Okunoye, KY Mok, SY Lim, ...
Movement Disorders 37 (8), 1593-1604, 2022
312022
Axin regulates dendritic spine morphogenesis through Cdc42-dependent signaling
Y Chen, Z Liang, E Fei, Y Chen, X Zhou, W Fang, WY Fu, AKY Fu, NY Ip
PloS one 10 (7), e0133115, 2015
282015
Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population
X Zhou, Y Chen, FCF Ip, NCH Lai, YYT Li, Y Jiang, H Zhong, Y Chen, ...
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 12 (1 …, 2020
262020
Polygenic score models for Alzheimer’s disease: from research to clinical applications
X Zhou, YYT Li, AKY Fu, NY Ip
Frontiers in Neuroscience 15, 650220, 2021
242021
Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study
M Rizig, S Bandres-Ciga, MB Makarious, OO Ojo, PW Crea, OV Abiodun, ...
The Lancet Neurology 22 (11), 1015-1025, 2023
232023
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer’s disease
P Xu, JC Chang, X Zhou, W Wang, M Bamkole, E Wong, K Bettayeb, ...
Journal of Experimental Medicine 218 (8), e20202446, 2021
232021
APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease intervention
X Zhou, AKY Fu, NY Ip
Current Opinion in Neurobiology 69, 58-67, 2021
212021
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction
X Zhou, Y Chen, FCF Ip, Y Jiang, H Cao, G Lv, H Zhong, J Chen, T Ye, ...
Communications Medicine 3 (1), 49, 2023
17*2023
Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
JJ Kim, D Vitale, DV Otani, MM Lian, K Heilbron, H Iwaki, J Lake, ...
Nature genetics 56 (1), 27-36, 2024
162024
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's disease
Y Jiang, X Zhou, HY Wong, L Ouyang, FCF Ip, V Chau, SF Lau, W Wu, ...
Nature Aging, 2022
142022
Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer’s Disease
Y Chen, J Xu, X Zhou, S Liu, Y Zhang, S Ma, AKY Fu, NY Ip, Y Chen
ACS chemical neuroscience 10 (9), 3986-3996, 2019
142019
Multi‐Omics‐Based Autophagy‐Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology
JC Park, N Barahona‐Torres, SY Jang, KY Mok, HJ Kim, SH Han, KH Cho, ...
Advanced Science 9 (23), 2201212, 2022
92022
Association of SPI1 haplotypes with altered SPI1 gene expression and Alzheimer’s disease risk
H Cao, X Zhou, Y Chen, FCF Ip, Y Chen, NCH Lai, R Lo, EPS Tong, ...
Journal of Alzheimer's Disease 86 (4), 1861-1873, 2022
92022
SNP2Vec: Scalable Self-Supervised Pre-Training for Genome-Wide Association Study
S Cahyawijaya, T Yu, Z Liu, TTW Mak, X Zhou, NY Ip, P Fung
arXiv preprint arXiv:2204.06699, 2022
52022
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