| Anti‐PEG immunity: emergence, characteristics, and unaddressed questions Q Yang, SK Lai Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 7 (5 …, 2015 | 582 | 2015 |
| Analysis of pre-existing IgG and IgM antibodies against polyethylene glycol (PEG) in the general population Q Yang, TM Jacobs, JD McCallen, DT Moore, JT Huckaby, JN Edelstein, ... Analytical Chemistry 88 (23), 11804-11812, 2016 | 284 | 2016 |
| Evading immune cell uptake and clearance requires PEG grafting at densities substantially exceeding the minimum for brush conformation Q Yang, SW Jones, CL Parker, WC Zamboni, JE Bear, SK Lai Molecular pharmaceutics 11 (4), 1250-1258, 2014 | 283 | 2014 |
| Anti-tumor activity of splice-switching oligonucleotides JA Bauman, SD Li, A Yang, L Huang, R Kole Nucleic acids research 38 (22), 8348-8356, 2010 | 154 | 2010 |
| Targeted nanoparticles deliver siRNA to melanoma Y Chen, SR Bathula, Q Yang, L Huang Journal of Investigative Dermatology 130 (12), 2790-2798, 2010 | 141 | 2010 |
| Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells Y Chen, J Sen, SR Bathula, Q Yang, R Fittipaldi, L Huang Molecular pharmaceutics 6 (3), 696-705, 2009 | 121 | 2009 |
| Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus CE Henry, YY Wang, Q Yang, T Hoang, S Chattopadhyay, T Hoen, ... Acta Biomaterialia 43, 61-70, 2016 | 69 | 2016 |
| How does the cell overcome LCP nanoparticle-induced calcium toxicity? YC Tseng, A Yang, L Huang Molecular pharmaceutics 10 (11), 4391-4395, 2013 | 44 | 2013 |
| Cross-Reactivity of Select PEG-Binding Antibodies to Other Polymers Containing a CCO Backbone J McCallen, J Prybylski, Q Yang, SK Lai ACS Biomaterials Science & Engineering 3 (8), 1605-1615, 2017 | 27 | 2017 |
| Addressing challenges of heterogeneous tumor treatment through bispecific protein-mediated pretargeted drug delivery Q Yang, CL Parker, JD McCallen, SK Lai Journal of Controlled Release 220, 715-726, 2015 | 25 | 2015 |
| Pretargeting with bispecific fusion proteins facilitates delivery of nanoparticles to tumor cells with distinct surface antigens Q Yang, CL Parker, Y Lin, OW Press, SI Park, SK Lai Journal of Controlled Release 255, 73-80, 2017 | 20 | 2017 |
| Engineering well-characterized PEG-coated nanoparticles for elucidating biological barriers to drug delivery Q Yang, SK Lai Cancer Nanotechnology: Methods and Protocols, 125-137, 2017 | 16 | 2017 |
| Multivalent interactions between streptavidin-based pretargeting fusion proteins and cell receptors impede efficient internalization of biotinylated nanoparticles CL Parker, Q Yang, B Yang, JD McCallen, SI Park, SK Lai Acta biomaterialia 63, 181-189, 2017 | 8 | 2017 |
| Statistical Approaches for Establishing Appropriate Immunogenicity Assay Cut Points: Impact of Sample Distribution, Sample Size, and Outlier Removal J Garlits, S McAfee, JA Taylor, E Shum, Q Yang, E Nunez, K Kameron, ... The AAPS Journal 25 (3), 37, 2023 | 3 | 2023 |
| Exploring and harnessing PEG-immune system interactions to engineer targeted stealth nanoparticles Q Yang The University of North Carolina at Chapel Hill, 2016 | 1 | 2016 |
| Polymer coated particles and methods thereof SK Lai, Q Yang US Patent 9,802,967, 2017 | | 2017 |
