| Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma GS Zode, MH Kuehn, DY Nishimura, CC Searby, K Mohan, SD Grozdanic, ... The Journal of clinical investigation 121 (9), 2011 | 295 | 2011 |
| Effects of TGF-β2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma RJ Wordinger, DL Fleenor, PE Hellberg, IH Pang, TO Tovar, GS Zode, ... Investigative ophthalmology & visual science 48 (3), 1191-1200, 2007 | 256 | 2007 |
| Consensus recommendations for trabecular meshwork cell isolation, characterization and culture KE Keller, SK Bhattacharya, T Borrás, TM Brunner, S Chansangpetch, ... Experimental eye research 171, 164-173, 2018 | 236 | 2018 |
| CRISPR-Cas9–based treatment of myocilin-associated glaucoma A Jain, G Zode, RB Kasetti, FA Ran, W Yan, TP Sharma, K Bugge, ... Proceedings of the National Academy of Sciences 114 (42), 11199-11204, 2017 | 182 | 2017 |
| Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma GS Zode, AB Sharma, X Lin, CC Searby, K Bugge, GH Kim, AF Clark, ... The Journal of clinical investigation 124 (5), 1956-1965, 2014 | 155 | 2014 |
| Mechanosensitive release of adenosine 5′‐triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A … JM Beckel, AJ Argall, JC Lim, J Xia, W Lu, EE Coffey, EJ Macarak, ... Glia 62 (9), 1486-1501, 2014 | 151 | 2014 |
| Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma GS Zode, KE Bugge, K Mohan, SD Grozdanic, JC Peters, DR Koehn, ... Investigative ophthalmology & visual science 53 (3), 1557-1565, 2012 | 126 | 2012 |
| Role of TGFβ/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins A Sethi, A Jain, GS Zode, RJ Wordinger, AF Clark Investigative ophthalmology & visual science 52 (8), 5251-5259, 2011 | 102 | 2011 |
| Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway GS Zode, A Sethi, AM Brun-Zinkernagel, IF Chang, AF Clark, ... Molecular vision 17, 1745, 2011 | 98 | 2011 |
| Bone morphogenetic protein 4 inhibits TGF‐β2 stimulation of extracellular matrix proteins in optic nerve head cells: Role of gremlin in ECM modulation GS Zode, AF Clark, RJ Wordinger Glia 57 (7), 755-766, 2009 | 92 | 2009 |
| Increased endoplasmic reticulum stress in human glaucomatous trabecular meshwork cells and tissues JC Peters, S Bhattacharya, AF Clark, GS Zode Investigative ophthalmology & visual science 56 (6), 3860-3868, 2015 | 89 | 2015 |
| Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork RB Kasetti, P Maddineni, JC Millar, AF Clark, GS Zode Scientific Reports 7 (1), 14951, 2017 | 80 | 2017 |
| Dexamethasone-induced ocular hypertension in mice: effects of myocilin and route of administration GC Patel, TN Phan, P Maddineni, RB Kasetti, JC Millar, AF Clark, ... The American journal of pathology 187 (4), 713-723, 2017 | 79 | 2017 |
| Focus on molecules: gremlin RJ Wordinger, G Zode, AF Clark Experimental eye research 87 (2), 78, 2008 | 76 | 2008 |
| Transforming growth factor β2 (TGFβ2) signaling plays a key role in glucocorticoid-induced ocular hypertension RB Kasetti, P Maddineni, PD Patel, C Searby, VC Sheffield, GS Zode Journal of Biological Chemistry 293 (25), 9854-9868, 2018 | 75 | 2018 |
| Expression of mutant myocilin induces abnormal intracellular accumulation of selected extracellular matrix proteins in the trabecular meshwork RB Kasetti, TN Phan, JC Millar, GS Zode Investigative ophthalmology & visual science 57 (14), 6058-6069, 2016 | 57 | 2016 |
| Glaucomatous cell derived matrices differentially modulate non-glaucomatous trabecular meshwork cellular behavior VK Raghunathan, J Benoit, R Kasetti, G Zode, M Salemi, BS Phinney, ... Acta biomaterialia 71, 444-459, 2018 | 56 | 2018 |
| Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye W Lu, HL Hu, J Sévigny, TG B'Ann, PL Kaufman, EC Johnson, ... Investigative ophthalmology & visual science 56 (5), 3075-3083, 2015 | 56 | 2015 |
| CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma P Maddineni, RB Kasetti, PD Patel, JC Millar, C Kiehlbauch, AF Clark, ... Molecular Neurodegeneration 15, 1-20, 2020 | 52 | 2020 |
| Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension Z Daneva, C Marziano, M Ottolini, YL Chen, TM Baker, M Kuppusamy, ... Proceedings of the National Academy of Sciences 118 (17), e2023130118, 2021 | 51 | 2021 |
