- ►uiowa.edu [PDF] RN Weinreb, PT Khaw - The Lancet, 2004 - Elsevier Primary open-angle glaucoma is a progressive optic neuropathy and, perhaps, the
most common form of glaucoma. Because the disease is treatable, and because the
visual impairment caused by glaucoma is irreversible, early detection is ... Cited by 190 - Related articles - All 14 versions
N Ziai, JW Dolan, RD Kacere, RF Brubaker - Archives of Ophthalmology, 1993 - archopht.highwire.org Objective: To study the effects of a topically applied prostaglandin
F2\g=a\analogue, PhXA41 (Latanoprost; 13,14\x=req-\ dihydro-17-phenyl-18,19,20-
trinor-prostaglandin F2\g=a\\x=req-\ isopropyl ester), on aqueous dynamics ... Cited by 177 - Related articles - BL Direct - All 3 versions
HK Mishima, K Masuda, Y Kitazawa, I Azuma, … - Archives of Ophthalmology, 1996 - archopht.highwire.org Methods: A total of 184 patients with primary open\x=req-\ angle glaucoma or
ocular hypertension at 35 medical cen- ters participatedin this randomized
double-masked study. The patients were randomized to receive either 0.005% ... Cited by 122 - Related articles - BL Direct - All 4 versions
CB Toris, CB Camras, ME Yablonski, RF … - Survey of ophthalmology, 1997 - Elsevier Topical prostaglandins (PGs) are very effective at reducing intraocular pressure
(IOP) in a variety of animals and in humans with relatively few side effects.
The mechanisms of action of several PGs, their prodrugs and analogues have ... Cited by 74 - Related articles - BL Direct - All 8 versions
B Fristrom, SEG Nilsson - Archives of Ophthalmology, 1993 - archopht.highwire.org \s=b\ Objective.\p=m-\To evaluate the effects of PhXA41, a new prostaglandin
analogue, on the intraocular pressure (IOP) in pa- tients receiving pilocarpine
treatment and the effects of pilocarpine in patients re- ceiving PhXA41 ... Cited by 73 - Related articles - BL Direct - All 5 versions
- ►iovs.org [PDF] RF Brubaker - Investigative Ophthalmology & Visual Science, 1991 - ARVO Early in this century, the aqueous humor was re- garded as a stagnant fluid, 1
but several important ob- servations laid this misconception to rest. The first
was the experiment done by Seidel 2 ' 3 and published in 1921 in which he ... Cited by 69 - Related articles - All 2 versions
- ►bmj.com [PDF] J Villumsen, A Alm - British Medical Journal, 1992 - bjo.bmj.com Abstract PhXA34, a prostaglandin analogue, was given topically to 40 patients
with untreated ocular hypertension in a double masked randomised study. One
single dose of 0 3, 1, 3, 10 gIg, or placebo (vehicle) was given to one eye ... Cited by 45 - Related articles - All 8 versions
P Racz, MR Ruzsonyi, ZT Nagy, LZ Bito - Archives of Ophthalmology, 1993 - archopht.highwire.org \s=b\ To eliminate uncertainties about com- pliance, 15 patients with glaucoma
(in- traocular pressure [IOP] >22 mm Hg and <40 mm Hg) were hospitalized to
partici- pate in a clinical trial of the ocular hypoten- sive effectiveness ... Cited by 43 - Related articles - BL Direct - All 5 versions
P Mukhopadhyay, TE Geoghegan, RV Patil, P … - Biochemical pharmacology, 1997 - Elsevier We have examined the expression of three prostaglandin (PG) receptors, EP 2 , EP
4 , and FP, in a nonpigmented ciliary epithelial cell line (ODMC1-2) and in
human ciliary muscle (HCM) cells. Total RNA preparations from either ... Cited by 37 - Related articles - BL Direct - All 4 versions
CB Camras, A Alm - Survey of ophthalmology, 1997 - Elsevier Several prostaglandins (PGs), their prodrugs, and their analogues have been
shown to reduce intraocular pressure (IOP) in normotensive volunteers and in
patients with elevated IOP. Initial clinical trials demonstrated efficacy ... Cited by 36 - Related articles - All 8 versions
