M Boulton, M Różanowska, B Różanowski - Journal of Photochemistry & Photobiology, B: Biology, 2001 - Elsevier The retina represents a paradox, in that, while light and oxygen are essential
for vision, these conditions also favour the formation of reactive oxygen
species leading to photochemical damage to the retina. Such light damage ... Cited by 106 - Related articles - All 6 versions
J Wu, S Seregard, PV Algvere - Survey of ophthalmology, 2006 - Elsevier Visual perception occurs when radiation with a wavelength between 400 and 760 nm
reaches the retina. The retina has evolved to capture photons efficiently and
initiate visual transduction. The retina, however, is vulnerable to damage ... Cited by 39 - Related articles - All 7 versions
J Kopitz, FG Holz, E Kaemmerer, F Schutt - Biochimie, 2004 - Elsevier In people over 50, age-related macular degeneration (ARMD) has become the most
common cause for severe visual loss and legal blindness in all industrialized
nations. Currently, there is no effective treatment for the majority of ... Cited by 36 - Related articles - All 3 versions
A Pawlak, M Różanowska, M Zareba, LE … - Archives of Biochemistry and Biophysics, 2002 - Elsevier The action spectra for the photoconsumption of oxygen by lipofuscin isolated
from human retinal pigment epithelium cells and liposomal suspensions containing
extracts of lipofuscin are reported. The lipofuscin and lipofuscin extract ... Cited by 18 - Related articles - BL Direct - All 3 versions
LE Lamb, M Zareba, SN Plakoudas, T Sarna, … - Archives of Biochemistry and Biophysics, 2001 - Elsevier Lipofuscin accumulation in the retinal pigment epithelium is associated with the
onset of age-related macular degeneration. Lipofuscin is phototoxic and affects
cellular function through the photochemical generation of reactive oxygen ... Cited by 11 - Related articles - BL Direct - All 5 versions
NM Haralampus-Grynaviski, LE Lamb, JD … - Photochemistry and Photobiology, 2001 - BioOne The emission spectra of single lipofuscin granules are examined using spectrally
resolved confocal microscopy and near-field scanning optical microscopy (NSOM).
The emission spectrum varies among the granules examined revealing that ... Cited by 10 - Related articles - BL Direct - All 5 versions
F Schutt, M Bergmann, FG Holz, S Dithmar, HE … - Graefe's Archive for Clinical and Experimental …, 2007 - Springer Page 1. LABORATORY INVESTIGATION Accumulation of A2-E in mitochondrial membranes
of cultured RPE cells Florian Schutt & Marion Bergmann & Frank G. Holz & ... Cited by 5 - Related articles - BL Direct - All 3 versions
S He, J Yaung, YH Kim, E Barron, SJ Ryan, … - Graefe's Archive for Clinical and Experimental …, 2008 - Springer Abstract Background Induction of glucose-regulated protein (GRP)- 78 in the
endoplasmic reticulum (ER) is a protective mechanism cells use to adapt to ER
stress. We evaluated the expression of GRP-78 and its regulation by an ... Cited by 3 - Related articles - BL Direct - All 4 versions