AB Roberts, F Tian, SDC Byfield, C Stuelten, … - Cytokine and Growth Factor Reviews, 2006 - Elsevier Smads2 and 3 transduce signals of TGF-β from the cell surface to the nucleus.
We used mice with a targeted deletion of Smad3 to study the specific
contributions of this signaling pathway to pathogenic effects of TGF-β. ... Cited by 67 - Related articles - All 12 versions
- ►iovs.org I Milenkovic, M Weick, P Wiedemann, A … - Investigative ophthalmology & visual science, 2003 - ARVO RESULTS. In Müller cells, the mitogenic effect of P2Y receptor activation by
extracellular adenosine triphosphate (ATP) depended on transactivation of both
the platelet-derived growth factor (PDGF) and the epidermal growth factor ... Cited by 49 - Related articles - BL Direct - All 6 versions
- ►iovs.org Y Ikuno, FL Leong, A Kazlauskas - Investigative ophthalmology & visual science, 2000 - ARVO PURPOSE. The work from numerous laboratories has led to the idea that the growth
factors such as platelet-derived growth factor (PDGF) contribute to
proliferative vitreoretinopathy (PVR) in experimental models of the ... Cited by 40 - Related articles - BL Direct - All 3 versions
S Saika, S Kono-Saika, T Tanaka, O Yamanaka … - Laboratory investigation, 2004 - nature.com Retinal pigment epithelial (RPE) cells dedifferentiate and undergo
epithelial–mesenchymal transition (EMT) following retinal detachment, playing
a central role in formation of fibrous tissue on the detached retina and ... Cited by 35 - Related articles - BL Direct - All 4 versions
R Simo, E Carrasco, M Garcia-Ramirez, C … - Current Diabetes Reviews, 2006 - ingentaconnect.com Abstract: Diabetic retinopathy continues to be the leading cause of legal
blindness among working-age individuals. The earliest histological features of
diabetic retinopathy include neuroretinal damage, capillary basement ... Cited by 34 - Related articles - BL Direct - All 2 versions
- ►iovs.org L Carrington, D McLeod, M Boulton - Investigative Ophthalmology & Visual Science, 2000 - ARVO METHODS. Cultured human RPE cells were seeded onto bovine retinal explants.
After attachment, cultures received one of the following exogenous growth
factors: platelet-derived growth factor (PDGF)-AB, PDGF-BB, basic ... Cited by 33 - Related articles - BL Direct - All 3 versions
JP Camiña, JF Campos, JE Caminos, C … - Journal of cellular physiology, 2007 - interscience.wiley.com In this work, we have evaluated the effect of the new discovered peptide
obestatin on cell proliferation in primary cultures of human retinal epithelial
cells (hRPE cells). The results showed that this peptide induced, in a dose- ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►iovs.org Y Ikuno, A Kazlauskas - Investigative ophthalmology & visual science, 2002 - ARVO METHODS. The dominant negative PDGFR (T R) is a truncated version of the
receptor, which does not have the intracellular domain. It was expressed by
using a retrovirus. In vitro characterization of T R was performed in ... Cited by 31 - Related articles - BL Direct - All 3 versions
EC La Heij, P Derhaag, F Hendrikse - Documenta Ophthalmologica, 2000 - Springer Abstract. Within the scope of a Retinal Fellowship of one year, we evaluated the
anatomic and functional results of scleral buckling operations in primary
rhegmatogenous retinal de- tachments. Eighty Consecutive non-selected ... Cited by 25 - Related articles - BL Direct - All 3 versions
- ►mcponline.org K Yamane, A Minamoto, H Yamashita, H … - Molecular & Cellular Proteomics, 2003 - ASBMB Purpose: Various protein contents such as enzymes, growth factors, and
structural components are responsible for biological activities in organs. We
have created a map of vitreous proteins and developed a proteome analysis ... Cited by 25 - Related articles - BL Direct - All 5 versions