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Scholar Results 1 - 10 of about 19 citing Kramer: Pigmented uveal tumours in a transgenic mouse model. (0.09 sec) 

Vasculogenic mimicry and tumor angiogenesis

- amjpathol.org
R Folberg, MJC Hendrix, AJ Maniotis - American Journal of Pathology, 2000 - ASIP
Tumors require a blood supply for growth and hematogenous dissemination. Much
attention has been focused on the role of angiogenesis—the recruitment of new
vessels into a tumor from pre-existing vessels. However, angiogenesis may ...
Cited by 320 - Related articles - BL Direct - All 5 versions

The state-of-the-art in chemoprevention of skin cancer


SP Stratton, RT Dorr, DS Alberts - European Journal of Cancer, 2000 - Elsevier
The incidence of skin cancer (both melanoma and non-melanoma) continues to grow
at an alarming rate. Our chemoprevention strategies include the development of
novel agents evaluated by (1) preclinical mechanistic studies in models of ...
Cited by 74 - Related articles - BL Direct - All 10 versions

Lack of BRAF mutations in uveal melanoma

- aacrjournals.org
D Rimoldi, S Salvi, D Lienard, FJ Lejeune, D … - Cancer research, 2003 - AACR
RAF proteins are serine/threonine kinases that mediate cellular responses to
growth signals by activating the mitogen-activated protein kinase pathway.
Mutations in the BRAF gene causing a V599E amino acid substitution that ...
Cited by 55 - Related articles - BL Direct - All 4 versions

Ocular melanoma: a review and the relationship to cutaneous melanoma


EA Hurst, JW Harbour, LA Cornelius - Archives of Dermatology, 2003 - archderm.highwire.org
Objectives The main objective of this review is to critically evaluate the
present evidence regarding a relationship between ocular melanoma (OM) and
cutaneous melanoma (CM). Melanomas are malignant neoplasms that develop ...
Cited by 24 - Related articles - BL Direct - All 13 versions

A new technique for implantation of tissue culture melanoma cells in a murine model of …


S Dithmar, D Rusciano, HE Grossniklaus - Melanoma Research, 2000 - journals.lww.com
Technique for implantation in a murine model of metastatic ocular melanoma
according to the Declaration of Helsinki and Guiding Principles in the Care and
Use of Animals (DHEW Publication, NIH 80-23). Tumours B16-LS9 murine ...
Cited by 20 - Related articles - BL Direct - All 2 versions

Transgenic mouse models for tumors of melanocytes and retinal pigment epithelium


F Beermann, A Hunziker, A Foletti - Pigment Cell Research, 1999 - interscience.wiley.com
Cutaneous and ocular melanomas are due to malignant transformation of neural
crest-derived melanocytes. The rising incidence of this tumor in humans has
stimulated experiments to devise suitable mouse models. In the past years, ...
Cited by 15 - Related articles - BL Direct - All 4 versions

Effectiveness of 1 {alpha}-Hydroxyvitamin D2 in Inhibiting Tumor Growth in a Murine …


DM Albert, A Kumar, SA Strugnell, SR … - Archives of Ophthalmology, 2004 - Am Med Assoc
Methods A total of 73 Tyr-Tag transgenic mice between 6 and 7 weeks old were
randomly assigned by sex and litter to 3 treatment groups to receive 0.05 µg/d,
0.1 µg/d, or 0.2 µg/d of 1 -OH-D 2 ; a control group received vehicle ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/-mice


WH Tolleson, JC Doss, J Latendresse, AR … - Archives of Ophthalmology, 2005 - archopht.highwire.org
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Cited by 9 - Related articles - BL Direct - All 4 versions

[PDF] Cutaneous melanoma in genetically modified animals


L Larue, F Beermann - Pigment Cell Research, 2007 - assets0.pubget.com
Cutaneous melanomas are tumors originating from skin melanocytes which are
present in hair follicles, and interfollicular epidermal and dermal layers.
Experimental work in model systems involves in sil- ico, in vitro and in ...
Cited by 10 - Related articles - View as HTML - BL Direct - All 4 versions

Tyr-TGF [alpha] transgenic mice develop ocular melanocytic lesions


R Sutton, C Gordon-Thomson, IA Cree, RS … - Melanoma Research, 2002 - journals.lww.com
Transforming growth factor-α (TGFα) has been implicated in melanocyte
transformation, as it is expressed in melanocytic lesions and in melanoma cells.
We investigated its role in melanoma development using a transgenic mouse ...
Cited by 6 - Related articles - BL Direct - All 2 versions


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