MR Hernandez - Progress in retinal and eye research, 2000 - Elsevier Primary open angle glaucoma is a common eye disease characterized by loss of the
axons of the retinal ganglion cells leading to progressive loss of vision. The
site of damage to the axons is at the level of the lamina cribrosa in the ... Cited by 156 - Related articles - All 5 versions
OA Agapova, CS Ricard, M Salvador-Silva, … - Glia, 2001 - interscience.wiley.com Glaucomatous optic neuropathy is a common blinding disease characterized by
remodeling of the extracellular matrix (ECM) and loss of retinal ganglion cell
(RGC) axons at the level of the optic nerve head (ONH). Astrocytes, the ... Cited by 72 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] - Free from Publisher NN Osborne, JPM Wood, G Chidlow, JH Bae, … - British Journal of Ophthalmology, 1999 - bjo.bmj.com Glaucomatous optic neuropathy is a chronic process which progresses over many
years. Data derived from clinical observations and from animal experiments
suggest that the axons of the optic nerve and the retinal ganglion cell ... Cited by 65 - Related articles - BL Direct - All 8 versions
MR Hernandez, OA Agapova, P Yang, M … - Glia, 2002 - interscience.wiley.com Recent advances in cDNA microarray technology have made it possible to analyze
expression of several thousand genes at the same time. Using this technique,
gene expression in human astrocytes cultured from glaucomatous and normal ... Cited by 66 - Related articles - BL Direct - All 3 versions
- ►iovs.org L Guo, SE Moss, RA Alexander, RR Ali, FW … - Investigative ophthalmology & visual science, 2005 - ARVO RESULTS. RGC apoptosis was significantly related to IOP exposure (integral IOP P
< 0.001; peak IOP P < 0.01). In the RGC layer, elevated IOP correlated
positively to a significant increase in MMP-9 activity (P < 0.001), tissue ... Cited by 56 - Related articles - All 9 versions
L Yuan, AH Neufeld - Journal of neuroscience research, 2001 - interscience.wiley.com To investigate the distribution and potential participation of microglia, the
resident defense cells of the central nervous system, in the optic nerve head
(ONH) in glaucoma, histological paraffin sections of optic nerves from ... Cited by 58 - Related articles - BL Direct - All 4 versions
RJ Wordinger, R Agarwal, M Talati, J Fuller, … - Mol Vis, 2002 - molvis.org Methods: Total RNA was isolated and subjected to reverse
transcriptase-polymerase chain reaction (RT-PCR) to examine the expression of
BMP, BMP receptor, and BMP associated proteins in tissues and cultured ... Cited by 54 - Related articles - Cached - All 3 versions
MF Cordeiro - Progress in Retinal and Eye Research, 2002 - Elsevier The introduction of the anti-cancer drugs Mitomycin and 5-fluorouracil as
anti-scarring agents within the last decade, has greatly improved surgical
results of glaucoma filtration surgery. However, a number of problems ... Cited by 48 - Related articles - All 4 versions
- ►iovs.org J Pena, O Agapova, B Gabelt, LA Levin, MJ … - Investigative ophthalmology & visual science, 2001 - ARVO METHODS. Unilateral, chronic elevated IOP was induced in 11 rhesus monkeys by
laser scarification of the trabecular meshwork. IOP was monitored weekly and
maintained within 25 to 45 mm Hg for 7 to 36 weeks. In 6 monkeys, ... Cited by 45 - Related articles - BL Direct - All 3 versions
MR Hernandez, JDO Pena, JA Selvidge, M … - Glia, 2000 - interscience.wiley.com Elastin is a major component of the extracellular matrix (ECM) of the lamina
cribrosa in the optic nerve head in humans and nonhuman primates. The lamina
cribrosa appears to be the site of damage to the retinal ganglion cell ... Cited by 44 - Related articles - BL Direct - All 3 versions
