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Scholar Results 1 - 10 of about 176 citing Tsubota: Treatment of dry eye by autologous serum application in Sjögren’s syndrome. (0.08 sec) 

Treatment of severe ocular-surface disorders with corneal epithelial stem-cell …

- stemcellgf.org [PDF] 
K Tsubota, Y Satake, M Kaido, N Shinozaki, S … - New England Journal …, 1999 - content.nejm.org
Methods We performed and evaluated 70 transplantations of corneal epithelial stem cells from
cadaveric eyes into 43 eyes of 39 patients with severe ocular-surface disorders and limbal
dysfunction. Medical treatment had failed in all patients. The patients had a mean ...
Cited by 253 - Related articles - BL Direct - All 11 versions

The diagnosis and management of dry eye: a twenty-five-year review


SC Pflugfelder, A Solomon, ME Stern - Cornea, 2000 - journals.lww.com
Supported in part by Public Health Service Research Grant EY11915, Department of Health
and Human Services, National Eye Institute, Bethesda Maryland, an unrestricted grant from Research
to Prevent Blindness and the Drs. David and Maureen Smith Ocular Surface and Tear ...
Cited by 179 - Related articles - BL Direct - All 3 versions

Update in Sjogren syndrome


RI Fox, M Stern, P Michelson - Current opinion in rheumatology, 2000 - journals.lww.com
Sjögren syndrome (SS), the second most common autoimmune rheumatic disease, refers to
keratoconjunctivitis sicca and xerostomia resulting from immune lymphocytes that infiltrate the
lacrimal and salivary glands. However, differential diagnosis remains confusing due to ...
Cited by 154 - Related articles - BL Direct - All 4 versions

Antiinflammatory therapy for dry eye


SC Pflugfelder - American journal of ophthalmology, 2004 - Elsevier
There is increasing evidence that decreased tear secretion, decreased tear turnover, and desiccation
promote inflammation on the ocular surface. An increase in soluble mediators (cytokines and
proteases) in the tear fluid, adhesion molecule expression by the conjunctival epithelium, ...
Cited by 140 - Related articles - All 21 versions

Treatment of persistent corneal epithelial defect by autologous serum application* …


K Tsubota, E Goto, S Shimmura, J Shimazaki - Ophthalmology, 1999 - Elsevier
Autologous serum was prepared from the patients and diluted to 20% by saline. The patients
were instructed to use the autologous serum six to ten times a day. The concentration of vitamin
A, epidermal growth factor (EGF), and transforming growth factor-β (TGF-β) was ...
Cited by 135 - Related articles - BL Direct - All 11 versions

Multilayered amniotic membrane transplantation for severe ulceration of the cornea …

- chula.ac.th [PDF] 
K Hanada, J Shimazaki, S Shimmura, K Tsubota - American journal of …, 2001 - Elsevier
METHODS: Ulcers were treated by amniotic membrane transplantation. Separate amniotic membranes
were transplanted as material to fill the stromal layer (amniotic membrane filling), as a basement
membrane (amniotic membrane graft), and as a wound cover (amniotic membrane ...
Cited by 122 - Related articles - BL Direct - All 12 versions

Autologous serum eyedrops for dry eyes and epithelial defects: clinical and in vitro …


AC Poon, G Geerling, JKG Dart, GE Fraenkel, JT … - British Journal of …, 2001 - bjo.bmj.com
RESULTS Autologous serum was used in 15 eyes of 13 patients with PED and 11 eyes of nine
patients with KCS. In two patients serum drops were started after penetrating keratoplasty
(PK). The PKs were performed for perforations secondary to PEDs. Of the 15 eyes with ...
Cited by 113 - Related articles - BL Direct - All 10 versions

The treatment of dry eye


M Calonge - Survey of ophthalmology, 2001 - Elsevier
The most widely used therapy for dry eye disease is tear replacement by topical artificial
tears. Punctal occlusion to prevent the drainage of natural or artificial tears is the most common
nonpharmacological treatment. These and other traditional therapies for dry eye disease ...
Cited by 88 - Related articles - BL Direct - All 7 versions

Autologous serum eye drops for ocular surface disorders


G Geerling, S Maclennan, D Hartwig - British Journal of Ophthalmology, 2004 - bjo.bmj.com
Tears have antimicrobial, nourishing, mechanical, and optical properties. They contain components
such as growth factors, fibronectin, and vitamins to support proliferation, migration, and differentiation
of the corneal and conjunctival epithelium. A lack of these epitheliotrophic factors—for ...
Cited by 81 - Related articles - BL Direct - All 12 versions

Comparison of autologous serum eye drops with conventional therapy in a …


BA Noble, RSK Loh, S MacLennan, K Pesudovs, … - British Journal of …, 2004 - bjo.bmj.com
Method: Patients fulfilling ophthalmological and haematological entry criteria were randomised
to either 3 months of autologous serum 50% followed by 3 months of their conventional
treatment, or 3 months of conventional treatment, followed by 3 months of autologous ...
Cited by 77 - Related articles - BL Direct - All 13 versions


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