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Scholar Results 1 - 10 of about 84 citing Rocha: Identification of androgen receptor protein and 5α-reductase mRNA in human ocular tissues. (0.10 sec) 

The pathology of dry eye


C Baudouin - Survey of ophthalmology, 2001 - Elsevier
Homeostasis of the tear film involves delicate hormonal and neuronal regulatory
mechanisms. The eye appears to be a target organ for sex hormones, particularly
the androgens, as they modulate the immune system and trophic functions of ...
Cited by 126 - Related articles - BL Direct - All 6 versions

Androgen deficiency, Meibomian gland dysfunction, and evaporative dry eye


DA Sullivan, BD Sullivan, JE Evans, F … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2002 - interscience.wiley.com
Abstract: Objective. We have recently discovered that women with primary and
secondary Sjögren's syndrome are androgen-deficient. We hypothesize that this
hormone insufficiency contributes to the meibomian gland dysfunction, tear ...
Cited by 101 - Related articles - BL Direct - All 5 versions

Androgens and dry eye in Sjögren's syndrome


DA Sullivan, LA Wickham, EM Rocha, KL … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 1999 - interscience.wiley.com
ABSTRACT: Sjögren's syndrome is an extremely complex and currently incurable
autoimmune disorder, which occurs primarily in females, and is associated with
lacrimal gland inflammation, meibomian gland dysfunction, and severe dry ...
Cited by 93 - Related articles - BL Direct - All 5 versions

Effect of androgen deficiency on the human meibomian gland and ocular surface

- endojournals.org
KL Krenzer, M Reza Dana, MD Ullman, JM … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc
The purpose of this study was to determine whether the chronic use of
antiandrogen medications leads to meibomian gland dysfunction, altered lipid
profiles in meibomian gland secretions, decreased tear film stability, and ...
Cited by 89 - Related articles - BL Direct - All 4 versions

The treatment of dry eye


M Calonge - Survey of ophthalmology, 2001 - Elsevier
The most widely used therapy for dry eye disease is tear replacement by topical
artificial tears. Punctal occlusion to prevent the drainage of natural or
artificial tears is the most common nonpharmacological treatment. These and ...
Cited by 87 - Related articles - BL Direct - All 7 versions

Functional aspects of the tear film lipid layer


AJ Bron, JM Tiffany, SM Gouveia, N Yokoi, … - Experimental eye research, 2004 - Elsevier
The lipid layer is an essential component of the tear film, providing a smooth
optical surface for the cornea and retarding evaporation from the eye. The
meibomian lipids which compose it are well adapted for this purpose. They ...
Cited by 85 - Related articles - All 3 versions

Androgen influence on the meibomian gland

- iovs.org
DA Sullivan, BD Sullivan, MD Ullman, EM … - Investigative ophthalmology & visual science, 2000 - ARVO
PURPOSE. The hypothesis in the study was that androgens control meibomian gland
function, regulate the quality and/or quantity of lipids produced by this
tissue, and promote the formation of the tear film's lipid layer. To test ...
Cited by 68 - Related articles - BL Direct - All 3 versions

Impact of antiandrogen treatment on the fatty acid profile of neutral lipids in human …

- endojournals.org
BD Sullivan, JE Evans, KL Krenzer, M Reza … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc
The purpose of this study was to determine whether the use of antiandrogen
medications is associated with significant alterations in the fatty acid (FA)
profiles of neutral lipids in human meibomian gland secretions. Meibomian ...
Cited by 48 - Related articles - BL Direct - All 5 versions

Complete androgen insensitivity syndrome: effect on human meibomian gland secretions

- aissg.org [PDF] 
BD Sullivan, JE Evans, JM Cermak, KL … - Archives of Ophthalmology, 2002 - Am Med Assoc
Methods Meibomian gland secretion samples were obtained from both eyes of (1)
women with complete androgen insensitivity syndrome, a condition characterized
by dysfunctional androgen receptors, and (2) age-matched female and male ...
Cited by 46 - Related articles - BL Direct - All 7 versions

Dry eye signs and symptoms in women with premature ovarian failure


JA Smith, S Vitale, GF Reed, SA Grieshaber, … - Archives of Ophthalmology, 2004 - Am Med Assoc
Results Women with POF scored significantly worse than controls on all ocular
surface damage parameters: Oxford score (3.2 vs 1.7; P = .001), conjunctival
lissamine green (2.1 vs 1.3; P = .02), corneal fluorescein staining (1.2 vs ...
Cited by 44 - Related articles - BL Direct - All 4 versions


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