S Haddad, CA Chen, SL Santangelo, JM … - Survey of ophthalmology, 2006 - Elsevier Age-related macular degeneration (AMD) is the leading cause of vision loss and
blindness among older adults in the USA and throughout the developed world.
Etiological research suggests that AMD is a complex disease, caused by the ... Cited by 93 - Related articles - All 3 versions
- ►nih.gov J Tuo, CM Bojanowski, CC Chan - Progress in retinal and eye research, 2004 - Elsevier Age-related macular degeneration (AMD) is a leading cause of blindness in the
United States and developed countries. Although the etiology and pathogenesis of
AMD remain unknown, a complex interaction of genetic and environmental ... Cited by 46 - Related articles - All 4 versions
PJ Oefner, CG Huber - Journal of Chromatography B, 2002 - Elsevier The introduction of alkylated, nonporous poly-(styrene–divinylbenzene)
microparticles in 1992 enabled the subsequent development of denaturing HPLC
that has emerged as the most sensitive screening method for mutations to ... Cited by 27 - Related articles - All 4 versions
F Simonelli, F Zarrilli, S Mazzeo, V Verde, N … - Clinica Chimica Acta, 2002 - Elsevier Objectives: The purpose of this study was to measure the oxidative and
antioxidant biochemical parameters in the serum of Italian patients with
age-related maculopathy (ARM) and in a similar age control group from the ... Cited by 14 - Related articles - All 6 versions
DW Schultz, RG Weleber, G Lawrence, S Barral … - Ophthalmic Genetics, 2005 - informahealthcare.com Age-related macular degeneration (AMD) is the most common blinding disorder in
the Western world. Similar to other common diseases in which age is a risk
factor (eg, type II diabetes or Alzheimer's disease), AMD is thought to ... Cited by 12 - Related articles - All 6 versions
CM Tang, PA Insel - Expert Opin. Ther. Targets, 2005 - Informa Pharma Science G-protein-coupled receptors (GPCRs), including 'orphan' GPCRs whose natural
ligands are unknown, comprise the largest membrane receptor superfamily and are
the most commonly used therapeutic targets. GPCR genetic loci har- bour ... Cited by 11 - Related articles - BL Direct - All 6 versions
A Ignatov, J Robert, C Gregory-Evans, HC … - British journal of pharmacology, 2006 - pubmedcentral.nih.gov Treatment of cells expressing GPR75 with subnanomolar concentrations of RANTES
led to stimulation of the luciferase activity in a reporter-gene assay, an
increase in inositol trisphosphate, and intracellular Ca 2+ . The latter ... Cited by 7 - Related articles - BL Direct - All 7 versions
HL Schulz, H Stoehr, K White, MA van Driel, … - Mol Vis, 2002 - molvis.org Purpose: Computer-assisted sampling of EST data contained within the UniGene
human sequences collection is being used to establish a catalog of novel genes
that are expressed exclusively or predominantly in the human retina. This ... Cited by 5 - Related articles - Cached - All 3 versions
JE Pease - British journal of pharmacology, 2006 - pubmedcentral.nih.gov Chemokines and their receptors play a central role in the trafficking of
leukocytes within the body, a process which is amenable to antagonism by small
molecules and which holds promise as a treatment for clinically important ... Cited by 1 - Related articles - BL Direct - All 4 versions