- ►jimmunol.org A Fukushima, T Yamaguchi, W Ishida, K Fukata … - The Journal of Immunology, 2005 - Am Assoc Immnol The 4-1BB receptor acts as a costimulator in CD8 + T cell activation. Agonistic
stimulation through this molecule by treatment with anti-4-1BB Abs has been
demonstrated to inhibit various experimentally induced diseases in animals. ... Cited by 33 - Related articles - BL Direct - All 4 versions
A Fukushima, A Ozaki, Z Jian, W Ishida, K … - Current Eye Research, 2005 - Informa Pharma Science Purpose: Allergic conjunctivitis is characterized by allergen-specific IgE in
the serum and infiltration of eosinophils into the conjunctiva. However, it
remains unclear whether early-phase reaction (EPR) mediated by Ag-specific ... Cited by 28 - Related articles - All 7 versions
- ►iovs.org A Fukushima, A Ozaki, K Fukata, W Ishida, H … - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. EC was induced in Brown Norway rats by injection of ovalbumin
(OVA)-specific T cells followed by OVA challenge with eye drops. Eyes, including
the conjunctivas, were harvested at different time points after challenge. ... Cited by 27 - Related articles - BL Direct - All 4 versions
A Leonardi, IA Fregona, M Plebani, AG Secchi … - Graefe's Archive for Clinical and Experimental …, 2006 - Springer Page 1. Graefe's Arch Clin Exp Ophthalmol (2006) 244: 1240–1245 CLINICAL
INVESTIGATION DOI 10.1007/s00417-006-0285-7 Andrea Leonardi ... Cited by 19 - Related articles - BL Direct - All 3 versions
- ►iovs.org ME Stern, K Siemasko, J Gao, A Duong, C … - Investigative ophthalmology & visual science, 2005 - ARVO METHODS. Wild-type BALB/c mice and IFN- knockout (KO) BALB/c mice were
sensitized in the footpad with short ragweed (SRW) allergen and challenged
topically for seven consecutive days with SRW allergen. The number of ... Cited by 17 - Related articles - BL Direct - All 3 versions
- ►nih.gov A Fukushima, T Yamaguchi, M Azuma, H … - British Medical Journal, 2006 - bjo.bmj.com Methods: EC was induced in Balb/c mice by active immunisation with short ragweed
pollen (RW) in alum. 10 days later (day 10), the mice were challenged with eye
drops containing RW. 24 hours after the challenge, conjunctivas, spleens, ... Cited by 16 - Related articles - BL Direct - All 6 versions
- ►iovs.org M Ueta, J Hamuro, M Yamamoto, K Kaseda, S … - Investigative ophthalmology & visual science, 2005 - ARVO RESULTS. I B –/– mice manifested chronic inflammation, specifically in the
ocular surface, but not in other tissues. In normal mice, I B was expressed in a
variety of mucosal tissues. The I B transcript was predominantly ... Cited by 15 - Related articles - All 5 versions
DA Groneberg, L Bielory, A Fischer, S Bonini … - Allergy, 2003 - interscience.wiley.com Allergic eye diseases are complex inflammatory conditions of the conjunctiva
with an increasing prevalence and incidence. The diseases are often concomitant
with other allergic diseases such as allergic rhinitis, atopic dermatitis ... Cited by 15 - Related articles - BL Direct - All 4 versions
A Ozaki, W Ishida, K Fukata, A Fukushima, H … - Microbiology and immunology, 2004 - J-STAGE Chronic AC comprises a spectrum of diseases includ- ing AKC and VKC which
compromise vision. Corneal ulceration and neovascularization are frequent conse-
quences of these chronic diseases, and treatment with a conventional mast ... Cited by 10 - Related articles - BL Direct - All 6 versions
A Fukushima, A Ozaki, K Fukata, H Ueno - Microbiology and immunology, 2003 - J-STAGE Hyperreactivity to innocuous environmental antigens in the conjunctiva leads to
allergic conjunctivitis (AC) (11). In the classical concept, IgE-mediated immune
responses are the major effector mechanism of allergic diseases (4, 20). ... Cited by 8 - Related articles - BL Direct - All 5 versions