DM Niedowicz, DL Daleke - Cell biochemistry and biophysics, 2005 - Springer The morbidity and mortality associated with diabetes is the result of the myriad complications
related to the disease. One of the most explored hypotheses to explain the onset of complications is
a hyperglycemia-induced increase in ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►iovs.org N Oishi, S Morikubo, Y Takamura, E Kubo, S Tsuzuki, … - … ophthalmology & visual …, 2006 - ARVO METHODS. The study involved 337 eyes of 337 patients with diabetes. The extent and severity of lens
opacity was assessed according to the Lens Opacities Classification System III (LOCS III). The AR
levels within RBCs were determined ... Cited by 7 - Related articles - BL Direct - All 3 versions
GB Reddy, A Satyanarayana, N Balakrishna, R … - Molecular …, 2008 - pubmedcentral.nih.gov Activation of polyol pathway due to increased aldose reductase (ALR2) activity has been implicated
in the development of diabetic complications including diabetic retinopathy (DR), a leading cause of
blindness. However, the ... Cited by 5 - Related articles - All 7 versions
AA Rao, H Thota, RS Gumpeny, A Akula, SB … - Medical Hypotheses, 2008 - Elsevier Diabetic retinopathy is the leading cause of blindness among patients with diabetes mellitus. We
evaluated the role of several proteins that are likely to be involved in diabetic retinopathy by
employing multiple sequence ... Cited by 1 - Related articles - All 27 versions
M Lorenzi, PJ Oates - Springer A BSTRACT The polyol pathway is a two-step metabolic pathway in which glucose is reduced to
sorbitol, which is then converted to fructose. Several biochemical features and a large body of data
implicate the polyol pathway as a ... Related articles
H Nambu, E Kubo, Y Takamura, S Tsuzuki, M … - Diabetes Research and …, 2008 - Elsevier Small interfering RNAs (siRNAs) were designed to target the coding sequence of rat AR-siRNA. RLECs
were cultured in either normal or high d-glucose. Western analysis was performed to monitor AR
expression. MTS (3-(4-5- ... Related articles - All 14 versions
P Mitchell, S Foran, E Assistance, J Foran - nhmrc.gov.au Guidelines for the Management of Diabetic Retinopathy ... ISBN Online: 1-74186-672-3 ISBN:
1-74186-671-5 Publications Number: 4176 ... Electronic publications This work is copyright. You may
download, display, print and ... Related articles - View as HTML - All 3 versions
M Lorenzi, PJ Oates - Diabetic Retinopathy, 2008 - books.google.com 6 The Polyol Pathway and Diabetic Retinopathy Mara Lorenzi and Peter J. Oates CONTENTS INTRODUCTION
BIOCHEMISTRY AND GENETICS OF THE POLYOL PATHWAY LEVEL OF EXPRESSION OF POLYOL PATHWAY ENZYMES AND
DIABETIC RETINOPATHY MECHANISMS OF ... Related articles