RT Libby, DB Gould, MG Anderson, SWM …, 2005 - Annual Reviews ▪ Abstract Glaucoma describes a group of diseases that kill retinal ganglion
cells. There are different types of glaucoma, and each appears to be genetically
heterogeneous. Different glaucoma genes have been identified, but these ... Cited by 62 - Related articles - All 7 versions
BJ Fan, DY Wang, DSC Lam, CP Pang - Clinical biochemistry, 2006 - Elsevier Over the past 10 years, there has been vigorous research on mapping the POAG
genes. The main technological approaches are functional cloning, family linkage
analysis, genome-wide scan, case-control association study, and microarray ... Cited by 53 - Related articles - All 3 versions
A Mukhopadhyay, M Acharya, S Mukherjee, J … - Mol Vis, 2002 - molvis.org Purpose: Glaucoma is the second leading cause of blindness worldwide after
cataract. Defects in the myocilin gene (MYOC) have been shown to be associated
with Primary Open Angle Glaucoma (POAG), the most common form of the ... Cited by 31 - Related articles - Cached - All 3 versions
AW Hewitt, JE Craig, DA Mackey - Clinical and Experimental Ophthalmology, 2006 - interscience.wiley.com Glaucoma, which is a complex heterogeneous disease, presents an ideal case for
genetic investigation. Primary open-angle glaucoma (POAG) is the commonest
subtype and will be the focus of this review. When detected early, POAG is ... Cited by 25 - Related articles - BL Direct - All 3 versions
M Acharya, S Mitra, A Mukhopadhyay, M … - Mol Vis, 2002 - molvis.org Purpose: Glaucoma is a complex neurodegenerative disorder of the eye. Primary
Open Angle Glaucoma (POAG) is the most common type, accounting for over half of
the total cases. Recently, a significant difference in the distribution of ... Cited by 19 - Related articles - Cached - All 3 versions
- ►bmj.com [PDF] T Ressiniotis, PG Griffiths, M Birch, S Keers, … - British Medical Journal, 2004 - jmg.bmj.com Page 1. doi:10.1136/jmg.2003.016089 2004;41;296-298 J. Med. Genet. T
Ressiniotis, PG Griffiths, M Birch, S Keers and PF Chinnery ... Cited by 15 - Related articles - BL Direct - All 7 versions
- ►iovs.org H Levkovitch-Verbin, R Dardik, S Vander, Y … - Investigative ophthalmology & visual science, 2006 - ARVO METHODS. A gene array of 18 signal transduction pathways was used to examine the
changes in RNA profiles of retinas post-ONT in rats. Among the seven genes that
were determined to be upregulated, four were confirmed to have higher ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►bmj.com DP Dimasi, AW Hewitt, CM Green, DA Mackey, … - British Medical Journal, 2005 - jmg.bmj.com Background: The final common pathway for open angle glaucoma (OAG) is retinal
ganglion cell apoptosis. Polymorphisms in p53, a major regulator of apoptosis,
affect the efficiency of cell death induction. Association studies of p53 ... Cited by 11 - Related articles - All 6 versions
HJ Lin, SC Tsai, FJ Tsai, WC Chen, JJP Tsai, … - Ophthalmologica, 2003 - content.karger.com Purpose: Genetic factors are known to play a role in the etiology of glaucoma.
More specifically, the role of the immune system is highly suspected. We
evaluated the association between 2 polymorphisms in the interleukin (IL) 1 ... Cited by 9 - Related articles - BL Direct - All 6 versions
