- ►iovs.org [PDF] KK Abu-Amero, J Morales, TM Bosley - Investigative ophthalmology & visual science, 2006 - ARVO G laucoma is the most common optic neuropathic process affecting humans and the
second most common cause of blindness worldwide. 1 Primary open-angle glaucoma
(POAG) is the most frequent type of glaucoma, with risk factors that ... Cited by 37 - Related articles - BL Direct - All 3 versions
- ►nih.gov NN Osborne, G Lascaratos, AJ Bron, G … - British Journal of Ophthalmology, 2006 - bjo.bmj.com The authors propose that light entering the eye interacts with retinal ganglion
cell (RGC) axon mitochondria to generate reactive oxygen intermediates (ROI) and
that when these neurons are in an energetically low state, their capacity ... Cited by 29 - Related articles - BL Direct - All 7 versions
X Qi, AS Lewin, L Sun, WW Hauswirth, J Guy - Annals of neurology, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►iovs.org EC Johnson, L Jia, WO Cepurna, TA Doser, … - Investigative ophthalmology & visual science, 2007 - ARVO METHODS. Unilateral sustained IOP elevation (glaucoma, n = 46) or optic nerve
transection (n = 10) was produced in rats. ONHs were removed, and the
retrobulbar optic nerves were graded for degeneration. Gene expression in ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►iovs.org X Qi, AS Lewin, L Sun, WW Hauswirth, J Guy - Investigative ophthalmology & visual science, 2007 - ARVO METHODS. Optic nerves from mice with EAE were probed for reactive oxygen species
(ROS) with the use of dichlorofluorescein diacetate (DCFDA), dihydroethidium,
and cerium chloride. To modulate mitochondrial oxidative stress, ... Cited by 21 - Related articles - BL Direct - All 3 versions
- ►iovs.org [PDF] KK Abu-Amero, TM Bosley - Investigative ophthalmology & visual science, 2006 - ARVO Khaled K. Abu-Amero 1 and Thomas M. Bosley 2,3,4 ... P URPOSE . To investigate
certain biochemical and molecular characteristics of mitochondria in patients
with Leber heredi- tary optic neuropathy (LHON)-like optic neuropathies. M ... Cited by 18 - Related articles - BL Direct - All 5 versions
- ►iovs.org AW Hewitt, SL Bennett, JH Fingert, RL … - Investigative ophthalmology & visual science, 2007 - ARVO METHODS. A case-control design was adopted. Sixty-six patients heterozygous for
a range of myocilin mutation (cases) were matched in disease severity to 105
patients with OAG known not to have a myocilin mutation (controls), using ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►iovs.org WK Ju, Q Liu, KY Kim, JG Crowston, JD … - Investigative ophthalmology & visual science, 2007 - ARVO METHODS. RGC-5 cells were differentiated with succinyl concanavalin A (50
µg/mL) and transferred to a pressurized incubator in which 30 mm Hg of pressure
was applied for 1, 2, or 3 days. As a control, differentiated cells from an ... Cited by 11 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org M Spinazzi, S Cazzola, M Bortolozzi, A … - Human molecular genetics, 2008 - Oxford Univ Press Autosomal dominant optic atrophy (ADOA), the commonest cause of inherited optic
atrophy, is caused by mutations in the ubiquitously expressed gene optic atrophy
1 (OPA1), involved in fusion and biogenesis of the inner membrane of ... Cited by 9 - Related articles - All 6 versions
NN Osborne, GY Li, D Ji, HJ Mortiboys, S … - Journal of Neurochemistry, 2008 - interscience.wiley.com Retinal ganglion cell axons within the globe are laden with mitochondria that
are unprotected from light (400–760 nm) impinging onto the retina. Light can
be absorbed by mitochondrial enzymes such as cytochrome and flavin oxidases ... Cited by 7 - Related articles - BL Direct - All 4 versions
