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Molecular genetics of AMD and current animal models


AO Edwards, G Malek - Angiogenesis, 2007 - Springer
Abstract During the past few years systematic investi- gation into the
epidemiology, genetics, and pathophysiol- ogy of age-related macular
degeneration (AMD) has provided important new insight into this leading ...
Cited by 22 - Related articles - BL Direct - All 3 versions

Plasma apolipoproteins and risk for age related maculopathy

- nih.gov
N Dashti, G McGwin, C Owsley, CA Curcio - British Medical Journal, 2006 - bjo.bmj.com
Methods: In a cross sectional study in a university clinic setting, 129 patients
(72 women and 57 men) underwent colour fundus photography, acuity and contrast
sensitivity assessment, and electroimmunoassays of plasma apolipoproteins B ...
Cited by 9 - Related articles - BL Direct - All 7 versions

ApoB100, LDLR-/-mice exhibit reduced electroretinographic response and cholesteryl esters …

- iovs.org
L Bretillon, N Acar, MW Seeliger, M Santos, … - Investigative Ophthalmology & Visual Science, 2008 - ARVO
1 From the INRA, UMR 1129 FLAVIC, Eye and Nutrition Research Group, F-21000
Dijon, France; the 3 Ocular Neurodegeneration Research Group, Centre for
Ophthalmology, Institute for Ophthalmic Research, Eberhard-Karls ...
Cited by 4 - Related articles - BL Direct - All 2 versions

Lipoprotein particles of intraocular origin in human Bruch membrane: an unusual lipid profile


L Wang, CM Li, M Rudolf, OV Belyaeva, BH … - Investigative Ophthalmology & Visual Science, 2009 - ARVO
RESULTS. EC was the largest component (32.4 ± 7.9 mol%) of BrM-LLP lipids. EC
was 11.3-fold more abundant than triglyceride (TG), unlike large apoB
lipoproteins in plasma. Of the fatty acids (FA) esterified to cholesterol, ...
Cited by 3 - Related articles - All 3 versions

The development of age-related macular degeneration (AMD) experimental models


W Jiang, GCY Chiou - 国际眼科杂志, 2007 - journal.shouxi.net
Age-related macular degeneration (AMD) is the leading cause of poor vision among
people aged over 65. It has many clinicopathologic signs, numerous pathogenesis
and various etiologies. The treatment for this disease is limited. Many ...
Cited by 2 - Related articles - Cached

Ultrastructural changes in a murine model of graded Bruch membrane lipoidal …

- iovs.org
U Schmidt-Erfurth, M Rudolf, M Funk, C … - Investigative Ophthalmology & Visual Science, 2008 - ARVO
RESULTS. Choriocapillaris, BM, RPE, and photoreceptors of standard diet control
animals showed a regular architecture. LDL-R –/– mice fed a standard diet
showed more diffuse focal alterations than control mice fed a high-fat ...
Cited by 1 - Related articles - BL Direct - All 2 versions

Genetic models of retinal degeneration and targets for gene therapy


BJ Song, SH Tsang, CS Lin - Gene Therapy and Molecular Biology, 2007 - gtmb.org
Studies utilizing animal models in combination with progress in the field of
molecular genetics have improved our understanding of pathways leading to
retinal degenerations. As a result, it has become clear that genes are ...
Related articles - Cached - All 4 versions

Genetic and modifiable risk factors for age-related macular degeneration


JJ Wang - Expert Review of Ophthalmology, 2006 - ingentaconnect.com
Age-related macular degeneration (AMD) is a leading cause of blindness in older
people. Research into AMD genes has had a major breakthrough recently with the
identification of a number of gene loci and single nucleotide polymorphisms ...
Related articles - BL Direct - All 3 versions

Morphologic and Electroretinographic Phenotype of SR-BI Knockout Mice after a Long-Term …


AC Provost, L Vede, K Bigot, N Keller, A … - Investigative Ophthalmology & Visual Science, 2009 - ARVO
1 From the Université Paris-Descartes, Faculté de Médecine
Paris-Descartes-site Necker, Centre de Recherche Thérapeutique en
Ophtalmologie, EA 2502 CERTO (Center de Recherches Thérapeutiques en ...
Related articles - All 3 versions

年龄相关性黄斑变性 (AMD) 实验模型的研究进展


江伟, 邱春亿 - 国际眼科杂志, 2007 - 万方数据资源系统
本文回顾了近年来各种不同的年龄相关性黄斑变性(AMD)的实验模型.其中应用最广泛的是激光
诱导脉络膜新生血管的形成(CNV),即渗出性AMD的晚期阶段.其它模型有的以本病不同病理 ...
Related articles - All 3 versions


 


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