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Scholar Results 1 - 10 of 11 citing Esfandiary: Association study of detoxification genes in age related macular degeneration. (0.07 sec) 

The genetics of age-related macular degeneration: a review of progress to date


S Haddad, CA Chen, SL Santangelo, JM … - Survey of ophthalmology, 2006 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of vision loss and
blindness among older adults in the USA and throughout the developed world.
Etiological research suggests that AMD is a complex disease, caused by the ...
Cited by 94 - Related articles - All 3 versions

Functional candidate genes in age-related macular degeneration: significant association …

- iovs.org
JL Haines, N Schnetz-Boutaud, S Schmidt, WK … - Investigative ophthalmology & visual science, 2006 - ARVO
PURPOSE. Age-related macular degeneration (AMD) is a retinal degenerative
disease that is the leading cause of blindness worldwide for individuals over
the age of 60. Although the etiology of AMD remains largely unknown, ...
Cited by 70 - Related articles - BL Direct - All 3 versions

Molecular genetics of AMD and current animal models


AO Edwards, G Malek - Angiogenesis, 2007 - Springer
Abstract During the past few years systematic investi- gation into the
epidemiology, genetics, and pathophysiol- ogy of age-related macular
degeneration (AMD) has provided important new insight into this leading ...
Cited by 22 - Related articles - BL Direct - All 3 versions

Progress in defining the molecular biology of age related macular degeneration


A Lotery, D Trump - Human Genetics, 2007 - Springer
Age related macular degeneration (AMD) is an extremely prevalent complex genetic
disorder. Its incidence rises exponentially in the elderly to a frequency of 1
in 2 in the general population by age 85. It aVects approximately 25 ...
Cited by 18 - Related articles - All 3 versions

Age-related macular degeneration: a perspective on genetic studies


N Patel, T Adewoyin, NV Chong - Eye, 2007 - nature.com
Age-related macular degeneration (AMD) is a common macular disease in the
developed world and recent studies have shown that specific genes may be
associated with it and may contribute to a higher risk of developing AMD.
Cited by 12 - Related articles - All 3 versions

Gene–environment interactions in ocular diseases


SC Sacca, C Bolognesi, A Battistella, A Bagnis, … - … Research-Fundamental and Molecular Mechanisms of …, 2009 - Elsevier
Glaucoma, in its degenerative form, is characterized by the degeneration of the
trabecular meshwork, the tissue of the anterior chamber of the eye devoted to
aqueous-humour outflow. Such a degenerative process results in intra-ocular ...
Cited by 3 - Related articles - All 3 versions

[PDF] The genetic and environmental factors involved in benzidine metabolism and bladder …


T Carreon, GK LeMasters, AM Ruder, PA … - Front Biosci, 2006 - bioscience.org
1. Abstract 2. Introduction 3. Workplace bladder cancer risk factors 4.
Benzidine exposure and bladder cancer 5. Benzidine metabolism 6. Metabolic
polymorphisms and bladder cancer 6.1. N-Acetyltransferases 6.2. Glutathione ...
Cited by 3 - Related articles - View as HTML - All 3 versions

Genotyping of eight polymorphic genes encoding drug-metabolizing enzymes and …


Y Lu, S Kow-Yin Kham, TC Foo, A Hany, TC … - Analytical biochemistry, 2007 - Elsevier
Polymorphisms in drug-metabolizing genes may lead to the production of
dysfunctional proteins and consequently affect therapeutic efficacy and toxicity
of drugs. Different frequencies of polymorphic alleles among the races have ...
Cited by 1 - Related articles - All 3 versions

Genetics of age-related macular degeneration


AYC Ting, TKM Lee, IM MacDonald - Current Opinion in Ophthalmology, 2009 - journals.lww.com
Introduction Age-related macular degeneration (AMD/ARMD) is the leading cause of
blindness in the developed world, resulting in significant vision impairment for
more than 1.75 million people in the United States alone. An estimated 30% ...
Related articles - All 4 versions

Microarray Analysis Identifies Changes in Inflammatory Gene Expression in Response to …


K Kurji, J Cui, T Lin, D Harriman, S Prasad, L … - Investigative Ophthalmology & Visual Science, 2009 - ARVO
Khaliq H. Kurji, 1,2 J. Cui, 1,2 T. Lin, 1 D. Harriman, 1 SS Prasad, 3 L. Kojic,
1,2 J. Matsubara 1,2 * ... Address: 1 Department of Ophthalmology and Visual
Sciences ... Biologics and Genetic Therapies Directorate, Health Canada
Related articles - All 2 versions


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