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Scholar Results 1 - 10 of about 18 citing Lai: Generation of transgenic mice with mild and severe retinal neovascularisation. (0.08 sec) 

Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo …

- cjb.net
U Kilic, E Kilic, A Jarve, Z Guo, A Spudich, … - Journal of Neuroscience, 2006 - neuro.cjb.net
Based on its trophic effects on neurons and vascular cells, vascular endothelial
growth factor (VEGF) is a promising candidate for the treatment of
neurodegenerative diseases. To evaluate the therapeutic potential of VEGF, ...
Cited by 44 - Related articles - All 16 versions

[PDF] Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization …


CM Lai, WY Shen, M Brankov, YKY Lai, NL … - changes - uq.edu.au
Chooi-May Lai,1,* Wei-Yong Shen,1,2 Meliha Brankov,1,2 Yvonne KY Lai,1,2 Nigel
L. Barnett,3 Shu-Yen Lee,4 Ian YS Yeo,4 Ranjana Mathur,4 Joseph ES Ho,4 Paul
Pineda,4 Amutha Barathi,4 Chong-Lye Ang,4 Ian J. Constable,1 and Elizabeth ...
Cited by 20 - Related articles - View as HTML - All 5 versions

Multiple Variants in Vascular Endothelial Growth Factor (VEGFA) Are Risk Factors for Time …

- shouxi.net
H Al-Kateb, L Mirea, X Xie, L Sun, M Liu, H … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—In a global multi-SNP test, there was a highly significant association
of VEGFA SNPs with severe retinopathy (P = 6.8 × 10 −5 )—the four other
outcomes were all nonsignificant. In survival analyses controlling for ...
Cited by 17 - Related articles - BL Direct - All 5 versions

AAV-mediated gene transfer for retinal diseases


M Allocca, A Tessitore, G Cotugno, A … - Expert Opin. Biol. Ther., 2006 - informahealthcare.com
Vectors based on the adeno-associated virus (rAAV) are able to transduce the
retina of animal models, including non-human primates, for a long-term period,
safely and at sustained levels. The ability of the various rAAV serotypes ...
Cited by 15 - Related articles - BL Direct - All 5 versions

Long-term global retinal microvascular changes in a transgenic vascular endothelial growth …


WY Shen, CM Lai, CE Graham, N Binz, YKY Lai … - Diabetologia, 2006 - Springer
Page 1. Diabetologia (2006) 49: 1690–1701 DOI 10.1007/s00125-006-0274-8 ARTICLE
W.-Y. Shen . CM Lai . CE Graham . N. Binz . YKY Lai . J. Eade . D. Guidolin . ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Early vascular and neuronal changes in a VEGF transgenic mouse model of retinal …

- iovs.org
PE van Eeden, LBG Tee, S Lukehurst, CM Lai … - Investigative ophthalmology & visual science, 2006 - ARVO
RESULTS. Rhodopsin was detected at P5 and reached mature levels by P15; VEGF
protein expression was transient, peaking at P10 to P15. In wild-type (wt) mice
at P7, vessels had formed in the nerve fiber/retinal ganglion cell layer ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Pathological heterogeneity of vasoproliferative retinopathy in transgenic mice …


W Shen, YKY Lai, C Lai, N Binz, LD Beazley, … - Advances in experimental medicine and biology, 2006 - Springer
Retinal neovascularization is a feature shared by many disease processes
including dia- betic retinopathy, retinopathy of prematurity, branch retinal
vein occlusion and central retinal vein occlusion, which are collectively ...
Cited by 2 - Related articles - BL Direct - All 5 versions

Characterisation of a model for retinal neovascularisation. VEGF model characterisation


PE van Eeden, L Tee, W Shen, S Lukehurst, C … - Advances in experimental medicine and biology, 2006 - Springer
Retinal neovascularisation is a major clinical complication of diabetic
retinopathy that takes place late in the disease process and constitutes the
most damaging phase resulting in loss of vision (Klein et al., 1984). ...
Cited by 2 - Related articles - BL Direct - All 4 versions

Role and Therapeutic Potential of VEGF in the Nervous System


R de Almodovar… - Physiological Reviews, 2009 - Am Physiological Soc
The development of the nervous and vascular systems constitutes primary events
in the evolution of the animal kingdom; the former provides electrical stimuli
and coordination, while the latter supplies oxygen and nutrients. Both ...
Cited by 1 - Related articles

Multiple variants in Vascular Endothelial Growth Factor (VEGF) are risk factors for time to …


A Paterson - Am Diabetes Assoc
Page 1. Page 1 of 20 Multiple variants in Vascular Endothelial Growth Factor
(VEGF) are risk factors for time to severe retinopathy ...
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