J Yeoh, J Sims, RH Guymer - Expert Opin. Pharmacother., 2006 - informahealthcare.com Age-related macular degeneration (AMD) is the leading cause of legal blindness
in people > 50 years of age in the developed world. AMD is both a debilitating
and costly disease for the individual and the community. Greater ... Cited by 5 - Related articles - BL Direct - All 4 versions
H Uchida, M Kuroki, T Shitama, H Hayashi, M … - Current Eye Research, 2008 - informahealthcare.com Purpose: Retinoic acid (RA) affects the activation of transforming growth
factor-β 1 (TGF-β 1) in a variety of cells. We have previously shown that
thrombospondin-1 (TSP-1) expression in retinal pigment epithelial (RPE) ... Cited by 4 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org P Lu, L Li, K Kuno, Y Wu, T Baba, Y Li, X … - The Journal of Immunology, 2008 - Am Assoc Immnol Macrophages accumulate during the course of corneal neovascularization, but its
mechanisms and roles still remain elusive. To address these points, we herein
examined corneal neovascularization after alkali injury in mice deficient ... Cited by 4 - Related articles - All 3 versions
- ►nih.gov Q Huang, S Wang, CM Sorenson, N Sheibani - Experimental eye research, 2008 - Elsevier Pigment epithelium derived factor (PEDF) is an endogenous inhibitor of
angiogenesis. However, its physiological role during vascular development and
neovascularization remains elusive. Here we investigated the role of PEDF ... Cited by 3 - Related articles - All 3 versions
IA Bhutto, K Uno, C Merges, L Zhang, DS … - Archives of Ophthalmology, 2008 - Am Med Assoc Methods Immunohistochemical analysis with antibodies against endostatin, pigment
epithelium–derived factor, and thrombospondin 1 was performed on the macular
region of aged control donor eyes (n = 8; mean age, 79.8 years) and eyes ... Cited by 3 - Related articles - BL Direct - All 4 versions
A Noël, M Jost, V Lambert, J Lecomte, JM … - Trends in Molecular Medicine, 2007 - cell.com Age-related macular degeneration (AMD) is the leading cause of blindness in
elderly patients. The more aggressive exudative form is characterized by
abnormal blood-vessel development that occurs beneath the retina as a ... Cited by 2 - Related articles - Cached - All 5 versions
S Wang, JL Gottlieb, CM Sorenson, N … - Archives of Ophthalmology, 2009 - Am Med Assoc Results We observed significant amounts of TSP-1 and PEDF in the vitreous
samples of control eyes. The TSP-1 levels varied in samples from patients with
diabetes. In contrast, PEDF levels showed little or no change in vitreous ... Related articles - All 2 versions
Y Wang, 2009 - ohiolink.edu Page 1. GENE DISCOVERY FOR AGE-RELATED MACULAR DEGENERATION by YANG WANG
Submitted in partial fulfillment of the requirements For ... Related articles - View as HTML - All 6 versions
JS Isenberg, WA Frazier, DD Roberts - Cellular and molecular life sciences: CMLS, 2008 - pubmedcentral.nih.gov Thrombospondin-1 is secreted protein that modulates vascular cell behavior via
several cell surface receptors. In vitro, nanomolar concentrations of
thrombospondin-1 are required to alter endothelial and vascular smooth ... Related articles
