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Scholar Results 1 - 10 of about 60 citing Khan: Smoking and age related macular degeneration: the number of pack years of cigarette.... (0.14 sec) 

Cigarette smoking strongly modifies the association of LOC387715 and age-related …

- nih.gov
S Schmidt, MA Hauser, WK Scott, EA Postel, … - The American Journal of Human Genetics, 2006 - Elsevier
We used iterative association mapping to identify a susceptibility gene for
age-related macular degeneration (AMD) on chromosome 10q26, which is one of the
most consistently implicated linkage regions for this disorder. We employed ...
Cited by 129 - Related articles - BL Direct - All 11 versions

Age-related macular degeneration

- puntodeencuentro.biz [PDF] 
RD Jager, WF Mieler, JW Miller - New England Journal of Medicine, 2008 - content.nejm.org
Age-related macular degeneration is the leading cause of irreversible blindness
in people 50 years of age or older in the developed world. 1 , 2 More than 8
million Americans have age-related macular degeneration, and the overall ...
Cited by 52 - Related articles - BL Direct - All 41 versions

Risk factors for five-year incident age-related macular degeneration: the Reykjavik Eye …


A Arnarsson, T Sverrisson, E Stefánsson, H … - American journal of ophthalmology, 2006 - Elsevier
Current alcohol consumption decreased the risk for drusen. Being married rather
than divorced or widowed decreased the risk for soft drusen; being single
decreased the risk of hypopigmentation as compared with being divorced or ...
Cited by 30 - Related articles - All 21 versions

A polymorphism of LOC387715 gene is associated with age-related macular degeneration …


S Tanimoto, H Tamura, T Ue, K Yamane, H … - Neuroscience letters, 2007 - Elsevier
Age-related macular degeneration (AMD) is one of the leading causes of blindness
among older adults in developed countries and also in Japan. Previous research
suggests that AMD is etiologically a complex disease, caused by multiple ...
Cited by 20 - Related articles - All 3 versions

Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial …

- iovs.org
L Jia, Z Liu, L Sun, SS Miller, BN Ames, CW … - Investigative ophthalmology & visual science, 2007 - ARVO
RESULTS. Acute acrolein exposure exceeding 50 µM (24 hours) in ARPR19 cells
caused toxicity, including decreases in cell viability, mitochondrial potential,
GSH, antioxidant capacity, Nrf2 expression, enzyme activity (mitochondrial ...
Cited by 18 - Related articles - BL Direct - All 4 versions

Oxidative stress modulates complement factor H expression in retinal pigmented epithelial …

- jbc.org
Z Wu, TW Lauer, A Sick, SF Hackett, PA … - Journal of Biological Chemistry, 2007 - ASBMB
Age-related macular degeneration (AMD), the leading cause of severe vision loss
in the elderly, is a complex disease that results from genetic modifications
that increase susceptibility to environmental exposures. Smoking, a major ...
Cited by 18 - Related articles - All 6 versions

Annual rates of arterial thromboembolic events in medicare neovascular age-related …


SL Alexander, WT Linde-Zwirble, W Werther, … - Ophthalmology, 2007 - Elsevier
Presented at: American Society of Retinal Specialists/European Society of
Retinal Specialists meeting, September 2006, Cannes, France, and American
Society of Retinal Specialists meeting, December 2007, Palm Springs, ...
Cited by 18 - Related articles - All 2 versions

Changes in select redox proteins of the retinal pigment epithelium in age-related macular …

- nih.gov
A Decanini, CL Nordgaard, X Feng, DA … - American journal of ophthalmology, 2007 - Elsevier
The pattern of protein changes identified in human donor tissue graded using the
MGS support the role of oxidative mechanisms in the pathogenesis and progression
of AMD. The MGS uses nearly identical clinical definitions and grading ...
Cited by 17 - Related articles - All 25 versions

Progress in defining the molecular biology of age related macular degeneration


A Lotery, D Trump - Human Genetics, 2007 - Springer
Age related macular degeneration (AMD) is an extremely prevalent complex genetic
disorder. Its incidence rises exponentially in the elderly to a frequency of 1
in 2 in the general population by age 85. It aVects approximately 25 ...
Cited by 16 - Related articles - All 3 versions

Age-related macular degeneration

- nih.gov
HR Coleman, CC Chan, FL Ferris, EY Chew - The Lancet, 2008 - Elsevier
Age-related macular degeneration is the leading cause of blindness in elderly
populations of European descent. The most consistent risk factors associated
with this ocular condition are increasing age and cigarette smoking. ...
Cited by 8 - Related articles - All 20 versions


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