- ►shouxi.net LL Molday, WWH Wu, RS Molday - Journal of Biological Chemistry, 2007 - ASBMB Retinoschisin or RS1 is a discoidin domain-containing protein encoded by the
gene responsible for X-linked retinoschisis (XLRS), an early onset macular
degeneration characterized by a splitting of the retina. Retinoschisin, ... Cited by 17 - Related articles - All 5 versions
SK Sikkink, S Biswas, NRA Parry, PE Stanga, … - British Medical Journal, 2007 - jmg.bmj.com X-linked retinoschisis is the leading cause of macular degeneration in males and
leads to splitting within the inner retinal layers leading to visual
deterioration. Many missense and protein truncating mutations have now been ... Cited by 17 - Related articles - BL Direct - All 5 versions
MA APUSHKIN, GA FISHMAN - Retina, 2006 - journals.lww.com From the Department of Ophthalmology and Visual Sciences, University of Illinois
at Chicago, Chicago, Illinois. Supported by The Foundation Fighting Blindness
(Owings Mills, MD); The Grant Healthcare Foundation (Chicago, IL); Na- ... Cited by 13 - Related articles - BL Direct - All 3 versions
A Janssen, SH Min, LL Molday, N Tanimoto, … - Molecular Therapy, 2008 - nature.com Proof-of-concept for a successful adeno-associated virus serotype 5
(AAV5)-mediated gene therapy in X-linked juvenile retinoschisis (XLRS) has been
demonstrated in an established mouse model for this condition. The initial ... Cited by 8 - Related articles - All 4 versions
MF Steiner-Champliaud, J Sahel, D Hicks - Mol Vis, 2006 - molvis.org Methods: Western blotting and RT-PCR of isolated outer nuclear (photoreceptors),
inner nuclear and ganglion cell layers, and cell culture compartments were
performed to verify sites of Rs1 synthesis and distribution. Potential Rs1 ... Cited by 7 - Related articles - Cached - All 3 versions
L Shi, K Jian, ML Ko, D Trump, GYP Ko - Journal of Biological Chemistry, 2009 - ASBMB The L-type voltage-gated calcium channels (L-VGCCs) are activated under high
depolarization voltages. They are vital for diverse biological events, including
cell excitability, differentiation, and synaptic transmission. In retinal ... Cited by 6 - Related articles - All 3 versions
- ►iovs.org FM Dyka, RS Molday - Investigative ophthalmology & visual science, 2007 - ARVO PURPOSE. X-linked retinoschisis (XLRS) is an early-onset retinal disease caused
by mutations in retinoschisin (RS1), a multisubunit, extracellular protein
implicated in retinal cell adhesion. Delivery of the normal RS1 gene to ... Cited by 5 - Related articles - BL Direct - All 3 versions
- ►nih.gov LS Kim, W Seiple, GA Fishman, JP Szlyk - Documenta Ophthalmologica, 2007 - Springer Abstract Purpose To determine whether retinal dysfunc- tion in obligate carriers
of X-linked retinoschisis (XLRS) could be observed in local electroretino-
graphic responses obtained with the multifocal electroretinogram (mfERG). ... Cited by 3 - Related articles - BL Direct - All 6 versions
M Zeng, C Yi, X Guo, X Jia, Y Deng, J Wang, … - Current Eye Research, 2007 - informahealthcare.com X-linked juvenile retinoschisis (XLRS) is a major cause of macular degeneration
in young men. In this study we analyzed all six exons of the XLRS1 gene in four
sporadic XLRS patients and in an affected family in China who were recently ... Cited by 2 - Related articles - BL Direct - All 5 versions
B Suganthalakshmi, D Shukla, A Rajendran, R … - Molecular Vision, 2007 - pubmedcentral.nih.gov X-linked juvenile retinoschisis (XLRS) is the leading cause of macular
degeneration in males. This condition is caused by mutations in the RS1 gene and
is, characterized by schisis within the retina. The purpose of this study ... Cited by 2 - Related articles - All 4 versions
