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Scholar Results 1 - 10 of about 17 citing Paskowitz: Light and inherited retinal degeneration. (0.11 sec) 

Retinal laminar architecture in human retinitis pigmentosa caused by rhodopsin gene …

- iovs.org
TS Aleman, AV Cideciyan, A Sumaroka, EAM … - Investigative Ophthalmology & Visual Science, 2008 - ARVO
RESULTS. Class A patients had only cone-mediated vision. The outer nuclear layer
(ONL) thinned with eccentricity and was not detectable within 3 to 4 mm of the
fovea. Scotomatous extracentral retina showed loss of ONL, thickening of ...
Cited by 14 - Related articles - BL Direct - All 2 versions

Reduced-illuminance autofluorescence imaging in ABCA4-associated retinal degenerations

- nih.gov
AV Cideciyan, M Swider, TS Aleman, MI … - Journal of the Optical Society of America A, 2007 - opticsinfobase.org
Received July 31, 2006; revised September 21, 2006; accepted September 26, 2006;
posted October 2, 2006 (Doc. ID 73260); published April 11, 2007 The health of
the retinal pigment epithelium (RPE) can be estimated with autofluorescence ...
Cited by 13 - Related articles - BL Direct - All 29 versions

Increased sensitivity to light-induced damage in a mouse model of autosomal dominant …

- iovs.org
DA White, WW Hauswirth, S Kaushal, AS … - Investigative ophthalmology & visual science, 2007 - ARVO
METHODS. Mice were bred to express the hT17M rhodopsin transgene in a line that
was hemizygous null for wild-type mouse rhodopsin (mrho +/– ), and the eyes of
transgenic mice and nontransgenic littermates were exposed for 2.5 minutes ...
Cited by 8 - Related articles - BL Direct - All 4 versions

The status of cones in the rhodopsin mutant P23H-3 retina: light-regulated damage and repair …

- iovs.org
V Chrysostomou, J Stone, S Stowe, NL Barnett … - Investigative Ophthalmology & Visual Science, 2008 - ARVO
METHODS. P23H-3 rats were raised in scotopic cyclic (12 hours of 5 lux, 12 hours
of dark) ambient light. At postnatal day 90 to 130, some were transferred to
photopic conditions (12 hours of 300 lux, 12 hours of dark) for 1 week and ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus …

- cjb.net
BM Tam, OL Moritz - Journal of Neuroscience, 2007 - neuro.cjb.net
To elucidate the molecular mechanisms underlying the light-sensitive retinal
degeneration caused by the rhodopsin mutation P23H, which causes retinitis
pigmentosa (RP) in humans, we expressed Xenopus laevis, bovine, human, and ...
Cited by 5 - Related articles - All 3 versions

Conserved interactions of a compact highly active enhancer/promoter upstream of the …


JE Young, EM Kasperek, TM Vogt, A Lis, SC … - Genomics, 2007 - Elsevier
Rhodopsin kinase (RK) is a conserved component of the light adaptation and
recovery pathways shared among rod and cone photoreceptors of a variety of
species. To gain insight into transcriptional mechanisms driving RK and ...
Cited by 4 - Related articles - All 4 versions

The potential of ambient light restriction to restore function to the degenerating P23H-3 rat …


K Valter, DK Kirk, J Stone - Advances in experimental medicine and biology, 2008 - Springer
Reviewing, in 1999, the non-genetic factors that regulate retinal degeneration,
we (Stone et al., 1999) hypothesized that the loss of vision during degeneration
results only partly from photoreceptor death. Significant visual loss ...
Cited by 2 - Related articles - BL Direct - All 4 versions

Retinitis pigmentosa


DG Telander, MD Anthony de Beus, KW Small - members.medscape.com
Overview: Retinitis pigmentosa (RP) is a group of inherited disorders characterized
by progressive peripheral vision loss and night vision difficulties (nyctalopia ...
Cited by 1 - Related articles - Cached - All 3 versions

Biochemical Defects Associated with Genetic Mutations in the Retina-Specific ABC …


EE Biswas-Fiss - Ocular Transporters in Ophthalmic Diseases and Drug …, 2008 - Springer
The retina-specific ABC transporter, ABCR, has been implicated in a wide
spectrum of inherited macular degenerations including Stargardt disease (STGD),
fundus flavimacula- tus (FFM) and autosomal recessive cone-rod dystrophy, ...
Related articles - All 2 versions

Steroids Do Not Prevent Photoreceptor Degeneration in the Light-Exposed T4R Rhodopsin …


D Gu, WA Beltran, S Pearce-Kelling, Z Li, GM … - Investigative Ophthalmology & Visual Science, 2009 - ARVO
METHODS. The dogs were dark adapted overnight, eyes dilated with mydriatics; the
right eye was light occluded and the fundus of the left eye photographed (
15–17 overlapping frames) with a fundus camera. For biochemical studies, ...
Related articles - All 3 versions


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