- ►oxfordjournals.org A Swaroop, KEH Branham, W Chen, G … - Human molecular genetics, 2007 - Oxford Univ Press Age-related macular degeneration (AMD) is a progressive neurodegenerative
disease, which affects quality of life for millions of elderly individuals
worldwide. AMD is associated with a diverse spectrum of clinical ... Cited by 46 - Related articles - BL Direct - All 6 versions
RJ Ross, V Verma, KI Rosenberg, CC Chan, J … - Expert review of ophthalmology, 2007 - pubmedcentral.nih.gov Age-related macular degeneration (AMD) is the leading cause of visual impairment
and blindness in the USA. Although the treatment of AMD has evolved to include
laser photocoagulation, photodynamic therapy, surgical macular ... Cited by 15 - Related articles - BL Direct - All 4 versions
J Jakobsdottir, YP Conley, DE Weeks, RE … - PloS one, 2008 - pubmedcentral.nih.gov Age-related maculopathy (ARM) is a common cause of visual impairment in the
elderly populations of industrialized countries and significantly affects the
quality of life of those suffering from the disease. Variants within two ... Cited by 11 - Related articles - All 7 versions
- ►iovs.org I Kaur, S Katta, A Hussain, N Hussain, A … - Investigative Ophthalmology & Visual Science, 2008 - ARVO RESULTS. Resequencing revealed seven different SNPs in these genes, of which
significant associations were noted with the risk alleles of rs10490924 (T
allele; P = 5.34 x 10 –12 ) in LOC387715, and rs11200638 (A allele; P = ... Cited by 7 - Related articles - BL Direct - All 2 versions
C Xing, TA Sivakumaran, JJ Wang, E … - Genes and Immunity, 2008 - nature.com Complement factor H (CFH) is a key regulator of the alternative pathway of
complement and its mutations have been associated with membranoproliferative
glomerulonephritis type II, atypical hemolytic uremic syndrome and ... Cited by 6 - Related articles - BL Direct - All 3 versions
RK Shuler, S Schmidt, P Gallins, MA Hauser, … - American Journal of Ophthalmology, 2007 - Elsevier The number of AMD cases in each group was 164 cases (two risk alleles), 330
cases (one risk allele), and 281 cases (zero risk allele). The mean age at
examination for homozygous carriers of the LOC387715 risk allele was ... Cited by 5 - Related articles - All 22 versions
I Droz, I Mantel, A Ambresin, M Faouzi, DF … - British Journal of Ophthalmology, 2008 - bjo.bmj.com Results: In this Swiss population, an OR of 2.95 was confirmed for AMD in the
presence of at least one risk C allele and OR of 9.05 for the CC homozygotes,
corrected for age and sex. No difference was found between the AMD stages. ... Cited by 4 - Related articles - BL Direct - All 4 versions
I Chowers, Y Cohen, N Goldenberg-Cohen, J … - Molecular Vision, 2008 - pubmedcentral.nih.gov The Tyr402His variant of complement factor H (CFH) is associated with
age-related macular degeneration (AMD) in several populations. Our aim was to
evaluate if this single nucleotide polymorphism (SNP) is associated with ... Cited by 3 - Related articles - All 6 versions
H Nakanishi, N Gotoh, R Yamada, K Yamashiro, … - Eye, 2009 - nature.com Highly myopic elderly Japanese patients with and without CNV were genotyped for
three AMD-associated single nucleotide polymorphisms (SNPs), namely rs10490924
(A69S) of ARMS2, rs11200638 of HTRA1, and rs1061170 (Y402H) of complement ... Related articles - All 3 versions