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Scholar Results 1 - 10 of about 22 citing Ashworth: Fibrillin and the eye. (0.09 sec) 

Elastic fibres

- biologists.org
CM Kielty, MJ Sherratt, CA Shuttleworth - Journal of cell science, 2002 - jcs.biologists.org
Elastic fibres are essential extracellular matrix macromolecules comprising an
elastin core surrounded by a mantle of fibrillin-rich microfibrils. They endow
connective tissues such as blood vessels, lungs and skin with the critical ...
Cited by 213 - Related articles - BL Direct - All 4 versions

Fibrillin: from microfibril assembly to biomechanical function

- nih.gov [PDF] 
CM Kielty, C Baldock, D Lee, MJ Rock, JL … - Philosophical Transactions: Biological Sciences, 2002 - rstb.royalsocietypublishing.org
Page 1. doi: 10.1098/rstb.2001.1029 , 207-217 357 2002 Phil. Trans. R. Soc. Lond.
B CM Kielty, C. Baldock, D. Lee, MJ Rock, JL Ashworth and CA Shuttleworth ...
Cited by 32 - Related articles - BL Direct - All 10 versions

Fibrillin-rich microfibrils: elastic biopolymers of the extracellular matrix

- mit.edu [PDF] 
CM Kielty, TJ Wess, L Haston, JL Ashworth, MJ … - Journal of muscle research and cell motility, 2002 - Springer
Fibrillin-rich microfibrils are evolutionarily ancient macromolecular assemblies
of the extracellular matrix. They have unique extensible properties that endow
vascular and other tissues with long-range elasticity. Microfibril ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Homotypic fibrillin-1 interactions in microfibril assembly


A Marson, MJ Rock, SA Cain, LJ Freeman, A … - Journal of Biological Chemistry, 2005 - ASBMB
We have defined the homotypic interactions of fibrillin-1 to obtain new insights
into microfibril assembly. Dose-dependent saturable high affinity binding was
demonstrated between N-terminal fragments, between furin processed ...
Cited by 23 - Related articles - All 7 versions

Latent TGFβ binding protein-1 and fibrillin-1 in human capsular opacification and in cultured …

- nih.gov [PDF] 
S Saika, T Miyamoto, T Tanaka, I Ishida, Y … - British Journal of Ophthalmology, 2001 - bjo.bmj.com
BACKGROUND/AIM It was previously reported that collagenous extracellular matrix
(ECM) in human capsular opacification contained isoforms of transforming growth
factor β (TGFβ). In the present study, the authors performed ...
Cited by 22 - Related articles - BL Direct - All 7 versions

Cornea in Marfan disease: Orbscan and in vivo confocal microscopy analysis

- iovs.org
G Sultan, C Baudouin, O Auzerie, M De Saint … - Investigative ophthalmology & visual science, 2002 - ARVO
METHODS. This prospective, clinical, comparative case series included 60 eyes of
31 patients with MFS and 32 eyes of 17 control subjects. First, biomicroscopic
examination was conducted to search for ectopia lentis. Then, mean ...
Cited by 19 - Related articles - BL Direct - All 4 versions

Current concepts of ocular manifestations in Marfan syndrome


AY Nemet, EI Assia, DJ Apple, IS Barequet - Survey of ophthalmology, 2006 - Elsevier
The first diagnostic criteria were defined in 1956 and were revised in 1979. The
Berlin criteria, which were composed by a group of international geneticists,
were established in 1986. 7 In 1996 the criteria were revised again to the ...
Cited by 12 - Related articles - All 13 versions

Light-microscopy evaluation of zonular fiber morphology in dogs with glaucoma: secondary …


RA Morris, RR Dubielzig - Veterinary Ophthalmology, 2005 - interscience.wiley.com
Lens displacement resulting in secondary glaucoma is common in terrier breeds.
This study was carried out to evaluate whether light microscopy was useful in
detecting abnormal patterns in zonular fiber protein. Eyes from 63 dogs ...
Cited by 10 - Related articles - All 3 versions

Marfan syndrome-causing mutations in fibrillin-1 result in gross morphological alterations …

- jbc.org
KT Mellody, LJ Freeman, C Baldock, TA Jowitt … - Journal of Biological Chemistry, 2006 - ASBMB
Mutations in fibrillin-1 result in Marfan syndrome, which affects the
cardiovascular, skeletal and ocular systems. The multiorgan involvement and wide
spectrum of associated phenotypes highlights the complex pathogenesis ...
Cited by 10 - Related articles - All 6 versions

Evidence for the intramolecular pleating model of fibrillin microfibril organisation from single …


Y Lu, DF Holmes, C Baldock - Journal of molecular biology, 2005 - Elsevier
Fibrillin microfibrils endow mammalian connective tissues with elasticity and
are fundamental for the deposition of elastin. The microfibrils are 57 nm
periodic supramolecular protein polymers with a mass of 2.4 MDa per repeat. ...
Cited by 4 - Related articles - All 5 versions


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