- ►physiology.org O Strauss - Physiological reviews, 2005 - Am Physiological Soc Located between vessels of the choriocapillaris and light-sensitive outer
segments of the photoreceptors, the retinal pigment epithelium (RPE) closely
interacts with photoreceptors in the maintenance of visual function. ... Cited by 165 - Related articles - All 7 versions
F Rolling - Gene therapy, 2004 - nature.com Retinal degenerative diseases such as retinal macular degeneration and retinitis
pigmentosa constitute a broad group of diseases that all share one critical
feature, the progressive apoptotic loss of cells in the retina. There is ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►jneurosci.org C Grimm, A Wenzel, D Stanescu, M … - Journal of Neuroscience, 2004 - Soc Neuroscience Elevation of erythropoietin (Epo) concentrations by hypoxic preconditioning or
application of recombinant human Epo (huEpo) protects the mouse retina against
light-induced degeneration by inhibiting photoreceptor cell apoptosis. ... Cited by 45 - Related articles - BL Direct - All 6 versions
OL Moritz, BM Tam, DS Papermaster, T … - Journal of Biological Chemistry, 2001 - ASBMB To study rhodopsin biosynthesis and transportin vivo, we engineered a fusion
protein (rho-GFP) of bovine rhodopsin (rho) and green fluorescent protein (GFP).
rho-GFP expressed in COS-1 cells bound 11-cis retinal, generating a pigment ... Cited by 38 - Related articles - BL Direct - All 7 versions
A Auricchio, F Rolling - Current gene therapy, 2005 - ingentaconnect.com Abstract: Retinal gene transfer holds big promises for the treatment of
inherited and non-inherited blinding diseases, such as retinitis pigmentosa or
age-related macular degeneration. Key to the development of successful gene- ... Cited by 27 - Related articles - BL Direct - All 4 versions
JR Hetling, MS Baig-Silva - Neurological Research, 2004 - ingentaconnect.com Department of Bioengineering, University of Illinois at Chicago, Chicago, IL,
USA A number of prevalent eye diseases exist which may lead to partial or total
blindness, and for which there are currently no cures or means by which to ... Cited by 26 - Related articles - BL Direct - All 3 versions
K Yoshizawa, K Kiuchi, H Nambu, J Yang, H … - Graefe's Archive for Clinical and Experimental …, 2002 - Springer Abstract Background: The effect of a caspase-3 inhibitor on retinal de-
generation in C3H mice carrying the rd gene, a mutation of a rod-specific
phosphodiesterase, was investigated. Methods: A quantity of 2 mg/kg of ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►iovs.org J Wu, A Gorman, X Zhou, C Sandra, E Chen - Investigative ophthalmology & visual science, 2002 - ARVO METHODS. Cyclic light–raised Sprague-Dawley rats were exposed to 400 to 480 nm
light for 6 hours at an irradiance of 0.64 W/m 2 . The rats were then kept in
darkness for recovery and killed at scheduled time points from 0 hours up ... Cited by 23 - Related articles - BL Direct - All 4 versions
NN Osborne, G Chidlow, JPM Wood, KG … - Current Eye Research, 2001 - informahealthcare.com Loss of vision leading to blindness is commonly due to pho- toreceptor or
ganglion cell malfunction. No evidence exists to suggest that a lesion
associated with other retinal cell- types (Müller cells, horizontal cells, ... Cited by 23 - Related articles - BL Direct - All 5 versions
