J Ambati, A Anand, S Fernandez, E Sakurai, … - Nature medicine, 2003 - curriculum.usc.edu AMD is the principal cause of irreversible, registered legal blindness on three
continents1. It is characterized by progressive degeneration of the retina, RPE
and underlying choroid (the highly vascular tissue beneath the RPE), which ... Cited by 225 - Related articles - BL Direct - All 8 versions
R Klein, BEK Klein, MD Knudtson, TY Wong, … - American journal of ophthalmology, 2005 - Elsevier Standardized protocols for blood collection, measurement of markers,
administration of a questionnaire, and gradings of stereoscopic color fundus
photography to determine ARM were used. Standard univariate and ... Cited by 40 - Related articles - All 11 versions
MV Kalayoglu, D Bula, J Arroyo, ES Gragoudas, … - Graefe's Archive for Clinical and Experimental …, 2005 - Springer Abstract Age-related macular de- generation (AMD) is a leading cause of
blindness in the United States, and increasing evidence suggests that it is an
inflammatory disease. The prokaryotic obligate intracellular pathogen ... Cited by 36 - Related articles - BL Direct - All 2 versions
A Kijlstra, EC La Heij, F Hendrikse - Ocular Immunology and Inflammation, 2005 - informahealthcare.com Recent findings indicate that immunological factors are involved not only in the
pathogenesis of age-related macular degeneration (AMD), but also in its
treatment. Earlier data showing the presence of inflammatory cells in ... Cited by 32 - Related articles - All 6 versions
- ►oxfordjournals.org L Robman, O Mahdi, C McCarty, P Dimitrov, G … - American journal of epidemiology, 2005 - Oxford Univ Press Recent studies have found an association between exposure to Chlamydia
pneumoniae infection and risk of age-related macular degeneration (AMD). To
assess a potential risk of AMD progression posed by exposure to C. ... Cited by 32 - Related articles - All 7 versions
- ►oxfordjournals.org PN Baird, LD Robman, AJ Richardson, PN … - Human Molecular Genetics, 2008 - Oxford Univ Press A number of risk factors including the complement factor H (CFH) gene, smoking
and Chlamydia pneumoniae have been associated with age-related macular
degeneration (AMD). However, the mechanisms underlying how these risk ... Cited by 15 - Related articles - BL Direct - All 6 versions
W Kessler, CA Jantos, J Dreier, S Pavlovic - Acta Ophthalmologica Scandinavica, 2006 - pt.wkhealth.com Purpose: Age-related macular degeneration (AMD) is the most frequent cause of
severe visual impairment in western countries, but its aetiology remains
unclear. A growing body of evidence suggests that inflammation contributes ... Cited by 8 - Related articles - BL Direct - All 5 versions
- ►iovs.org L Robman, OS Mahdi, JJ Wang, G Burlutsky, P … - Investigative Ophthalmology & Visual Science, 2007 - ARVO METHODS. The BMES examined 3654 persons aged 49 to 97 years during 1992 through
1994 (BMES I survey). Survivors from this cohort (n = 2335; 75%) and 1174
persons who moved in this area or reached an eligible age were examined ... Cited by 6 - Related articles - BL Direct - All 3 versions
FC Barouch, JW Miller - International Ophthalmology Clinics, 2007 - journals.lww.com Age-related macular degeneration (AMD) affects more than 1.75 million
individuals in the United States and is the leading cause of blindness in
persons over the age of 65 in Western countries.1 The earliest signs of AMD ... Cited by 5 - Related articles - BL Direct - All 4 versions
R Klein, MD Knudtson, BEK Klein, TY Wong, … - Ophthalmology, 2008 - Elsevier To describe the relationship of systemic inflammatory disease, complement factor
H (CFH) Y402H (1277T→C) genotype status and age-related macular degeneration
(AMD) prevalence in a multiethnic population of whites, blacks, Hispanics, ... Cited by 5 - Related articles - All 23 versions
