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Scholar Results 1 - 10 of about 125 citing Fajans: Scope and heterogeneous nature of MODY.. (0.09 sec) 

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young


SS Fajans, GI Bell, KS Polonsky - New England Journal of Medicine, 2001 - content.nejm.org
Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group
of disorders characterized by nonketotic diabetes mellitus, an autosomal
dominant mode of inheritance, an onset usually before the age of 25 years ...
Cited by 506 - Related articles - BL Direct - All 7 versions

Familial hyperglycemia due to mutations in glucokinase--definition of a subtype of diabetes …


P Froguel, H Zouali, N Vionnet, G Velho, M … - New England Journal of Medicine, 1993 - content.nejm.org
Background and Methods Non-insulin-dependent diabetes mellitus (NIDDM) is a
genetically heterogeneous disorder. Maturity-onset diabetes of the young, a form
of NIDDM with an early age of onset and autosomal dominant inheritance, can ...
Cited by 475 - Related articles - BL Direct - All 6 versions

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent …


PH Froguel, M Vaxillaire, F Sun, G Velho, H …, 1992 - nature.com
NON-INSULIN-DEPENDENT diabetes mellitus (NIDDM) is a major health problem,
affecting 5% of the world population. Genetic factors are important in NIDDM,
but the mechanisms leading to glucose intolerance are unknown 1,2 . Genetic ...
Cited by 306 - Related articles - All 6 versions

Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young …

- pnas.org [PDF] 
GI Bell, KS Xiang, MV Newman, SH Wu, LG … - Proceedings of the National Academy of Sciences, 1991 - National Acad Sciences
Page 1. Proc. Nati. Acad. Sci. USA Vol. 88, pp. 1484-1488, February 1991
Genetics Gene for non-insulin-dependent diabetes mellitus ...
Cited by 190 - Related articles - All 11 versions

Characteristics of youth-onset noninsulin-dependent diabetes mellitus and insulin-dependent …


CR Scott, JM Smith, MM Cradock, C Pihoker - Pediatrics, 1997 - Am Acad Pediatrics
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Department of Pediatrics, University of Arkansas for Medical Sciences, ...
Cited by 181 - Related articles - BL Direct - All 5 versions

Mammalian glucokinase and its gene.


PB Iynedjian - Biochemical Journal, 1993 - pubmedcentral.nih.gov
Page 1. Biochem. J. (1993) 293,1-13 (Printed in Great Britain) REVIEW ARTICLE
Mammalian glucokinase and its gene Patrick B. IYNEDJIAN ...
Cited by 177 - Related articles - BL Direct - All 8 versions

Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations.

- nih.gov [PDF] 
MM Byrne, J Sturis, K Clement, N Vionnet, ME … - Journal of Clinical Investigation, 1994 - pubmedcentral.nih.gov
Pancreatic (-cell function was studied in six subjects with mu- tations in the
enzyme glucokinase (GCK) who were found to have elevated fasting and
postprandial glucose levels incompar- ison to six normoglycemic controls. ...
Cited by 162 - Related articles - BL Direct - All 6 versions

A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation …


TH Lindner, PR Njolstad, Y Horikawa, L Bostad … - Human Molecular Genetics, 1999 - Oxford Univ Press
Mutations in the homeodomain-containing transcription factor hepatocyte nuclear
factor (HNF)-1[beta] are the cause of one form of maturity-onset diabetes of the
young (MODY), type 5 (MODY5). We have studied a Norwegian family, N5, with ...
Cited by 155 - Related articles - BL Direct - All 8 versions

Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects.

- nih.gov [PDF] 
G Velho, KF Petersen, G Perseghin, JH … - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov
J. Clin. Invest. © The American Society for Clinical Investigation, Inc.
0021-9738/96/10/1755/07 $2.00 Volume 98, Number 8, October 1996, 1755–1761
... Impaired Hepatic Glycogen Synthesis in Glucokinase-deficient (MODY-2) ...
Cited by 152 - Related articles - BL Direct - All 10 versions

Glucokinase as pancreatic beta cell glucose sensor and diabetes gene.

- nih.gov [PDF] 
F Matschinsky, Y Liang, P Kesavan, L Wang, P … - Journal of Clinical Investigation, 1993 - pubmedcentral.nih.gov
Introduction This article is an account of research in physiological chemis-
try, molecular biology, and human genetics that developed the concept that
glucokinase(GK)' ofthe insulin-secreting pancre- atic /3 cells plays the ...
Cited by 151 - Related articles - BL Direct - All 5 versions


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