- ►harvard.edu [PDF] M Stumvoll, BJ Goldstein, TW van Haeften - The Lancet, 2005 - Elsevier Type 2 diabetes mellitus has become an epidemic, and virtually no physician is
without patients who have the disease. Whereas insulin insensitivity is an early
phenomenon partly related to obesity, pancreas β-cell function declines ... Cited by 433 - Related articles - All 17 versions
- ►diabetesjournals.org CM Damcott, TI Pollin, LJ Reinhart, SH Ott, H … - Diabetes, 2006 - Am Diabetes Assoc Transcription factor 7-like 2 (TCF7L2) regulates genes involved in cell
proliferation and differentiation. The TCF7L2 gene is located on chromosome
10q25 in a region of replicated linkage to type 2 diabetes. Recently, a ... Cited by 151 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org LE Wagenknecht, DW Bowden, JJ Carr, CD … - Diabetes, 2001 - Am Diabetes Assoc Type 2 diabetes is widely recognized as a major risk factor for atherosclerotic
cardiovascular disease, including subclinical atherosclerosis as measured by
noninvasive procedures. However, the role of genetic factors that ... Cited by 109 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org MI McCarthy - Human Molecular Genetics, 2004 - Oxford Univ Press The rapid increase in the prevalence of type 2 diabetes (T2D) represents a major
challenge for health care delivery worldwide. Identification of genes
influencing individual susceptibility to disease offers a route to better ... Cited by 94 - Related articles - All 4 versions
M Arcos-Burgos, M Muenke - Clinical genetics, 2002 - interscience.wiley.com Genetic isolates, as shown empirically by the Finnish, Old Order Amish,
Hutterites, Sardinian and Jewish communities among others, represent a most
important and powerful tool in genetically mapping inherited disorders. The ... Cited by 86 - Related articles - BL Direct - All 6 versions
S Sanna, AU Jackson, R Nagaraja, CJ Willer, … - Nature Genetics, 2008 - nature.com Identifying genetic variants that influence human height will advance our
understanding of skeletal growth and development. Several rare genetic variants
have been convincingly and reproducibly associated with height in mendelian ... Cited by 81 - Related articles - BL Direct - All 3 versions
- ►endojournals.org WC Hsueh, BD Mitchell, JL Schneider, PL St … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc To identify the genetic determinants of typical obesity, we performed a
genome-wide scan of obesity-related traits using data from the Amish. Multipoint
linkage analysis was performed using a variance components procedure on ... Cited by 70 - Related articles - BL Direct - All 7 versions
RZ Yang, MJ Lee, H Hu, TI Pollin, AS Ryan, … - PLoS Med, 2006 - medicine.plosjournals.org Acute-phase serum amyloid A (A-SAA) mRNA levels, and A-SAA adipose secretion and
serum levels were measured in obese and nonobese individuals, obese participants
who underwent weight-loss, and persons treated with the insulin sensitizer ... Cited by 74 - Related articles - Cached - All 11 versions
- ►diabetesjournals.org CM Damcott, SH Ott, TI Pollin, LJ Reinhart, J … - Diabetes, 2005 - Am Diabetes Assoc Adiponectin receptor 1 (ADIPOR1) and adiponectin receptor 2 (ADIPOR2) are newly
identified receptors for adiponectin, an adipocytokine with anti-inflammatory
and insulin-sensitizing properties. We screened for polymorphisms by ... Cited by 66 - Related articles - All 7 versions
MS Freeman, MW Mansfield, JH Barrett, PJ … - Diabetic Medicine, 2002 - pt.wkhealth.com Results: Adjusted for age, sex and body mass index, the traits showed
considerable heritability. For waist-hip ratio, heritability was 15%. The
heritabilities of fasting glucose, insulin and estimated insulin resistance ... Cited by 64 - Related articles - BL Direct - All 5 versions
