M Fasshauer, J Klein, S Neumann, M … - Biochemical and Biophysical Research …, 2002 - Elsevier Recently, it has been demonstrated that the fat-derived protein adiponectin is
an important insulin-sensitizing adipocytokine which is downregulated in insulin
resistance and obesity and replenishment of which in adiponectin-deficient ... Cited by 399 - Related articles - BL Direct - All 5 versions
M Fasshauer, R Paschke - Diabetologia, 2003 - Springer It has long been known that obesity and insulin resis- tance are linked.
Recently, it has been shown that adi- pocytes secrete several proteins including
tumour ne- crosis factor-α, interleukin-6, resistin, and adiponec- tin. ... Cited by 287 - Related articles - BL Direct - All 4 versions
M Fasshauer, J Klein, S Neumann, M … - Febs Letters, 2001 - Elsevier Recently, it has been shown that the fat-derived factor adiponectin is
downregulated in insulin resistance and obesity and that replenishment of this
adipocytokine reverses insulin resistance in mice. Growing evidence, on the ... Cited by 221 - Related articles - All 6 versions
- ►diabetesjournals.org J Krakoff, T Funahashi, CDA Stehouwer, CG … - Diabetes care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Participants with normal glucose tolerance at
baseline were selected. Case subjects (who later developed type 2 diabetes), and
control subjects (n = 71 pairs) were matched for BMI, age, and sex. ... Cited by 181 - Related articles - BL Direct - All 7 versions
- Free from Publisher RM Krauss - Diabetes Care, 2004 - Am Diabetes Assoc Insulin resistance and type 2 diabetes are associated with a clustering of
interrelated plasma lipid and lipoprotein abnormalities, which include reduced
HDL cholesterol, a predominance of small dense LDL particles, and elevated ... Cited by 182 - Related articles - BL Direct - All 6 versions
M Fasshauer, J Klein, S Neumann, M … - Biochemical and biophysical research communications, 2001 - Elsevier Resistin has recently been implicated as an adipocytokine leading to insulin
resistance and, therefore, potentially linking obesity and diabetes. To further
characterize the regulation of this fat-secreted protein by insulin ... Cited by 146 - Related articles - BL Direct - All 5 versions
SB Wheatcroft, IL Williams, AM Shah, MT … - Diabetic Medicine, 2003 - pt.wkhealth.com Background: Insulin resistance is a key component of the insulin resistance
syndrome and is a crucially important metabolic abnormality in Type 2 diabetes.
Insulin-resistant individuals are at significantly increased risk of ... Cited by 137 - Related articles - BL Direct - All 5 versions
S Müller, S Martin, W Koenig, P Hanifi- … - Diabetologia, 2002 - Springer Aims/hypothesis. A population-based sample was studied to define immune
abnormalities in individuals at risk of Type II (non-insulin-dependent) diabetes
mellitus because of impaired glucose tolerance. Methods. A total of 1653 ... Cited by 125 - Related articles - BL Direct - All 6 versions
J Frystyk - Growth hormone & IGF research, 2004 - Elsevier IGF-I is a multipotent growth factor with important actions on normal tissue
growth and regeneration. In addition, IGF-I has been suggested to have
beneficial effects on glucose homeostasis due to its glucose lowering and ... Cited by 107 - Related articles - All 5 versions
M Fasshauer, J Klein, S Neumann, M … - FEBS letters, 2001 - Elsevier Resistin was recently identified as a hormone secreted by adipocytes which leads
to insulin resistance in vivo and in vitro and might therefore be an important
link between obesity and diabetes. To clarify the regulation of resistin ... Cited by 100 - Related articles - All 5 versions