- ►kopernika.pl [PDF] EE Calle, R Kaaks - Nature Reviews Cancer, 2004 - medscape.com The prevalence of overweight and obesity in most developed countries (and in
urban areas of many less developed countries) has been increasing markedly over
the past two decades. [1] By the year 2000, nearly two-thirds of adults in ... Cited by 469 - Related articles - BL Direct - All 6 versions
- ►physiology.org FW Booth, MV Chakravarthy, SE Gordon, EE … - Journal of Applied Physiology, 2002 - Am Physiological Soc A hypothesis is presented based on a coalescence of anthropological estimations
of Homo sapiens' phenotypes in the Late Paleolithic era 10,000 years ago, with
Darwinian natural selection synergized with Neel's idea of the so-called ... Cited by 168 - Related articles - BL Direct - All 10 versions
F Ovalle, R Azziz - Fertility and sterility, 2002 - Elsevier Result(s): Insulin resistance affects between 10% and 25% of the general
population. Two common disorders frequently associated with IR are PCOS,
affecting 4% to 6% of reproductive-aged women, and type 2 diabetes ... Cited by 162 - Related articles - All 10 versions
Y Zick - Trends in cell biology, 2001 - Elsevier Insulin resistance refers to a decreased capacity of circulating insulin to
regulate nutrient metabolism. It is associated with the development of type 2
diabetes – an ever-increasing epidemic of the 21st century. Recent ... Cited by 156 - Related articles - BL Direct - All 8 versions
- ►onlinejacc.org JB Hermiller, A Raizner, L Cannon, PA … - Journal of the American College of Cardiology, 2005 - Elsevier Percutaneous coronary intervention in patients with diabetes is associated with
high rates of restenosis and repeat revascularization due to excessive
neointimal proliferation, a process that may be blunted with the ... Cited by 148 - Related articles - All 8 versions
- ►edulife.com.br [PDF] PJ Miranda, RA DeFronzo, RM Califf, JR … - American Heart Journal, 2005 - Elsevier In 1988, Reaven 1 proposed that insulin resistance is central to the etiology of
type 2 diabetes mellitus, hypertension, and coronary artery disease. The concept
of insulin resistance and associated metabolic abnormalities leading to ... Cited by 120 - Related articles - All 13 versions
- ►jbc.org MW Greene, H Sakaue, L Wang, DR Alessi, … - Journal of Biological Chemistry, 2003 - ASBMB Ser/Thr phosphorylation of insulin receptor substrate-1 (IRS-1) is a negative
regulator of insulin signaling. One potential mechanism for this is that Ser/Thr
phosphorylation decreases the ability of IRS-1 to be ... Cited by 116 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org GF Watts, PHR Barrett, J Ji, AP Serone, DC … - Diabetes, 2003 - Am Diabetes Assoc The metabolic syndrome is characterized by insulin resistance and abnormal
apolipoprotein AI (apoAI) and apolipoprotein B-100 (apoB) metabolism that may
collectively accelerate atherosclerosis. The effects of atorvastatin (40 ... Cited by 110 - Related articles - BL Direct - All 4 versions
ZM Younossi, T Gramlich, CA Matteoni, N … - Clinical Gastroenterology and Hepatology, 2004 - Elsevier Nonalcoholic fatty liver disease (NAFLD) is reported commonly in patients with
type 2 diabetes mellitus (DM), which has been suggested as a risk factor for the
progressive form of NAFLD, or nonalcoholic steatohepatitis. The aim of this ... Cited by 111 - Related articles - BL Direct - All 8 versions
