M Stumvoll, H Häring - Diabetes, 2002 - Am Diabetes Assoc Peroxisome proliferator-activated receptor (PPAR)-γ is a transcription factor
with a key role in adipocyte differentiation. The Ala allele of the common
Pro12Ala polymorphism in the isoform PPAR-γ2 is associated with reduced ... Cited by 187 - Related articles - BL Direct - All 5 versions
T Rankinen, L Pérusse, SJ Weisnagel, EE … - Obesity, 2002 - nature.com This report constitutes the eighth update of the human obesity gene map,
incorporating published results up to the end of October 2001. Evidence from the
rodent and human obesity cases caused by single-gene mutations, Mendelian ... Cited by 146 - Related articles - BL Direct - All 5 versions
- ►bmj.com S Masud, S Ye - British Medical Journal, 2003 - jmg.bmj.com Peroxisome proliferator activated receptor- (PPAR- ) is a transcription factor
abundantly expressed in adipocytes, and plays a key role in the regulation of
adipocyte differentiation, lipid storage, glucose homeostasis, and blood ... Cited by 86 - Related articles - BL Direct - All 6 versions
YM Cho, MD Ritchie, JH Moore, JY Park, KU … - Diabetologia, 2004 - Springer Aims/hypothesis. Type 2 diabetes mellitus is a com- plex genetic disease, which
results from interactions between multiple genes and environmental factors
without any single factor having strong independent effects. This study was ... Cited by 86 - Related articles - BL Direct - All 7 versions
- ►nih.gov J Millstein, DV Conti, FD Gilliland, WJ … - The American Journal of Human Genetics, 2006 - Elsevier An efficient testing strategy called the “focused interaction testing
framework” (FITF) was developed to identify susceptibility genes involved in
epistatic interactions for case-control studies of candidate genes. In the ... Cited by 72 - Related articles - BL Direct - All 16 versions
J Roth, X Qiang, SL Marbán, H Redelt, BC … - Obesity research, 2004 - sochob.cl Abstract ROTH, JESSE, XIAOLING QIANG, SHARON LEE MARA´ N, HENRY REDELT, AND
BARBARA C. LOWELL. The obesity pandemic: where have we been and where are we
going? Obes Res. 2004;12:88S–101S. Obesity, a new pandemic, is associated ... Cited by 69 - Related articles - View as HTML - All 6 versions
A Meirhaeghe, P Amouyel - Molecular Genetics and Metabolism, 2004 - Elsevier Peroxisome proliferator-activated receptor γ (PPARγ) is a transcription factor
with a key role in adipocyte differentiation. Since 1997, studies of rare
mutations and common polymorphisms of the PPARγ gene have enabled us to ... Cited by 64 - Related articles - All 3 versions
DM Evans, J Marchini, AP Morris, LR Cardon - PLoS Genet, 2006 - genetics.plosjournals.org Studies in model organisms suggest that epistasis may play an important role in
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R Rosmond - International journal of obesity, 2003 - nature.com During the past decade, mutations affecting liability to central obesity have
been discovered at a phenomenal rate, and despite few consistently replicated
findings, a number of intriguing results have emerged in the literature. ... Cited by 49 - Related articles - BL Direct - All 4 versions
CM Damcott, P Sack, AR Shuldiner - Endocrinology and metabolism clinics of North America, 2003 - Elsevier Obesity has become an epidemic in the United States and worldwide. The
1999–2000 National Health and Nutrition Examination Survey (NHANES) estimated
that 64% of the adult population of the United States is either overweight ... Cited by 48 - Related articles - BL Direct - All 3 versions
