- ►nih.gov H Vlassara, W Cai, J Crandall, T Goldberg, R … - Proceedings of the National Academy of Sciences of …, 2002 - National Acad Sciences Diet is a major environmental source of proinflammatory AGEs (heat-generated
advanced glycation end products); its impact in humans remains unclear. We
explored the effects of two equivalent diets, one regular (high AGE, H-AGE) ... Cited by 228 - Related articles - BL Direct - All 10 versions
PJ Thornalley - Archives of Biochemistry and Biophysics, 2003 - Elsevier Aminoguanidine (AG) is a prototype therapeutic agent for the prevention of
formation of advanced glycation endproducts. It reacts rapidly with
α,β-dicarbonyl compounds such as methylglyoxal, glyoxal, and ... Cited by 123 - Related articles - All 4 versions
- ►diabetesjournals.org A Stirban, M Negrean, B Stratmann, T … - Diabetes Care, 2006 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Thirteen people with type 2 diabetes were given a
heat-processed test meal with a high AGE content (HAGE; 15.100 AGE kU, 580 kcal,
54 g protein, 17 g lipids, and 48 g carbohydrates) before and after a 3-day ... Cited by 86 - Related articles - BL Direct - All 5 versions
KM Biemel, DA Friedl, MO Lederer - Journal of Biological Chemistry, 2002 - ASBMB Glycation reactions leading to protein modifications (advanced glycation end
products) contribute to various pathologies associated with the general aging
process and long term complications of diabetes. However, only few relevant ... Cited by 80 - Related articles - BL Direct - All 6 versions
LA Leiter, A Ceriello, JA Davidson, M … - Clinical therapeutics, 2005 - Elsevier About 33% of people diagnosed as having type 2 diabetes based on postprandial
hyperglycemia have normal FPG. PPG contributes ≥70% to the total glycemic load
in patients who are fairly well controlled (HbA, 1c ≤.3%). Furthermore, ... Cited by 76 - Related articles - All 4 versions
BF Liu, S Miyata, Y Hirota, S Higo, H … - Kidney international, 2003 - nature.com The formation of methylglyoxal (MG), a highly reactive dicarbonyl compound, is
accelerated through several pathways, including the glycation reaction under
diabetic conditions, presumably contributing to tissue injury in diabetes. ... Cited by 48 - Related articles - BL Direct - All 4 versions
- ►cnfindpark.cn M Negrean, A Stirban, B Stratmann, T … - American Journal of Clinical Nutrition, 2007 - ajcn.cnfindpark.cn Design: Twenty inpatients with T2DM [ (±SEM) age: 55.4 ± 2.2 y; glycated
hemoglobin: 8.8 ± 0.5%] were investigated. In a randomized crossover design,
the effects of a low-AGE (LAGE) and high-AGE (HAGE) meal on macrovascular ... Cited by 50 - Related articles - BL Direct - All 7 versions
M Portero-Otín, R Pamplona, MJ Bellmunt, MC … - Diabetes, 2002 - Am Diabetes Assoc Formation of advanced glycation end products (AGEs) is considered a potential
link between hyperglycemia and chronic diabetic complications, including
disturbances in cell signaling. It was hypothesized that AGEs alter cell ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►rug.nl [PDF] AJ Smit, HL Lutgers - Current medicinal chemistry, 2004 - ingentaconnect.com Abstract: Advanced glycation endproducts (AGE) are a class of compounds
resulting from glycation and oxidation of proteins, lipids or nucleic acids.
Glycation is the non-enzymatic addition or insertion of saccharide ... Cited by 41 - Related articles - BL Direct - All 10 versions
WC Duckworth - Current Atherosclerosis Reports, 2001 - Springer Cardiovascular Disease and Diabetes Cardiovascular disease is the major cause of
morbidity and mortality in patients with diabetes. CV complications are two to
six times greater than microvascular complications, and over 60% of all ... Cited by 37 - Related articles - All 3 versions
