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Scholar Results 1 - 10 of about 26 citing Metcalfe: Concordance for type 1 diabetes in identical twins is affected by insulin genotype. (0.13 sec) 

Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish …

- diabetesjournals.org
V Hyttinen, J Kaprio, L Kinnunen, M Koskenvuo, J … - Diabetes, 2003 - Am Diabetes Assoc
Finland has the world's highest incidence of type 1 diabetes, and it is steadily increasing. We
determined concordance rates and estimated heritability for type 1 diabetes in the Finnish Twin
Cohort, a population-based twin ...
Cited by 136 - Related articles - BL Direct - All 5 versions

Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin- …

- nih.gov
S Tracy, KM Drescher, NM Chapman, KS Kim, SD … - Journal of …, 2002 - Am Soc Microbiol
Insulin-dependent (type 1) diabetes mellitus (T1D) onset is mediated by individual human genetics as
well as undefined environmental influences such as viral infections. The group B coxsackieviruses
(CVB) are commonly named as ...
Cited by 51 - Related articles - BL Direct - All 9 versions

The insulin gene in diabetes


A Pugliese, D Miceli - Diabetes/Metabolism Reviews - interscience.wiley.com
Lack of insulin production or abnormalities affecting insulin secretion are key to the development
of almost all forms of diabetes, including the common type 1 (insulin-dependent) and type 2
(non-insulin-dependent) diabetes ...
Cited by 43 - Related articles - BL Direct - All 3 versions

Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: …

- unmc.edu [PDF] 
KM Drescher, K Kono, S Bopegamage, SD Carson, S … - Virology, 2004 - Elsevier
Group B coxsackieviruses (CVB) are believed to trigger some cases of human type 1 diabetes (T1D),
although the mechanism by which this may occur has not been shown. We demonstrated previously that
inoculation of young nonobese ...
Cited by 27 - Related articles - All 6 versions

Islet abnormalities in the pathogenesis of autoimmune diabetes

- cell.com
JGM Rosmalen, PJM Leenen, C Pelegri, HA … - Trends in Endocrinology & …, 2002 - Elsevier
Type 1 diabetes mellitus is a T-cell-mediated autoimmune disease that results in the destruction of
the insulin-producing β cells in the pancreatic islets of Langerhans. In spite of extensive genetic
and immunological studies, mainly ...
Cited by 27 - Related articles - All 7 versions

Impact of genetic and non-genetic factors in type 1 diabetes


MI Hawa, H Beyan, LR Buckley, RDG … - American journal of …, 2002 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets. In
this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the ...
Cited by 27 - Related articles - BL Direct - All 3 versions

Genetic determinants of type 1 diabetes across populations


MM Jahromi, GS Eisenbarth - ANNALS-NEW YORK ACADEMY …, 2006 - interscience.wiley.com
Abstract: T1D results from autoimmune-mediated destruction of the pancreatic β cells, a process
that is conditioned by multiple genes and environmental factors. The main genetic determinants map
to the major histocompatibility ...
Cited by 24 - Related articles - BL Direct - All 4 versions

A new expression of diabetes: double diabetes


P Pozzilli, R Buzzetti - Trends in Endocrinology & Metabolism, 2007 - Elsevier
Diabetes is on the increase worldwide. The incidence of both type 1 and type 2 diabetes has shown a
rise, in parallel with a notable increase in the incidence of a new expression of the disease in
children and adolescents, with the ...
Cited by 23 - Related articles - All 5 versions

Autoimmunity, environmental exposure and vaccination: is there a link?


G Ravel, M Christ, F Horand, J Descotes - Toxicology, 2004 - Elsevier
Although the wide clinical experience shows that vaccines are generally safe, concern has been
expressed for a causal link between vaccines and autoimmune diseases. Even though the mechanisms of
autoimmunity are ill-elucidated, ...
Cited by 17 - Related articles - All 4 versions

Hematopoietic stem cell therapy for type 1 diabetes: induction of tolerance and islet …


RK Burt, Y Oyama, A Traynor, NS Kenyon - Autoimmunity Reviews, 2002 - Elsevier
Diabetes is a chronic disease with significant morbidity and mortality. Pancreas or islet cell
transplantation is limited by a shortage of donors and chronic immune suppression to prevent
allograft rejection. Consequently, ...
Cited by 18 - Related articles - All 3 versions


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