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Scholar Results 1 - 10 of 12 citing Brändle: Diminished insulin secretory response to glucose but normal insulin and glucagon.... (0.33 sec) 

Molecular mechanisms of mitochondrial diabetes (MIDD)


JA Maassen, GMC Janssen, LM 't Hart - Annals of Medicine, 2005 - informahealthcare.com
Abstract Mitochondria provide cells with most of the energy in the form of
adenosine triphosphate (ATP). Mitochondria are complex organelles encoded both
by nuclear and mtDNA. Only a few mitochondrial components are encoded by ...
Cited by 38 - Related articles - All 6 versions

In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin …

- unige.ch [PDF] 
P Maechler, S Carobbio, B Rubi - International Journal of Biochemistry and Cell Biology, 2006 - Elsevier
Pancreatic beta-cells are unique neuroendocrine cells displaying the peculiar
feature of responding to nutrients, principally glucose, as primary stimulus.
This requires translation of a metabolic substrate into intracellular ...
Cited by 29 - Related articles - All 7 versions

Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways …

- unige.ch [PDF] 
PBM de Andrade, B Rubi, F Frigerio, JMW … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis Mitochondrial DNA (mtDNA) mutations cause several
diseases, including mitochondrial inherited diabetes and deafness (MIDD),
typically associated with the mtDNA A3243G point mutation on tRNALeu gene. ...
Cited by 24 - Related articles - BL Direct - All 4 versions

Effect of donor age on function of isolated human islets

- diabetesjournals.org
SH Ihm, I Matsumoto, T Sawada, M Nakano, … - Diabetes, 2006 - Am Diabetes Assoc
This study intended to evaluate the impact of donor age on the function of
isolated islets. Analysis of human islets from cadaveric donors (age 16–70
years) was performed using glucose-stimulated insulin release (GSIR) (n = ...
Cited by 22 - Related articles - BL Direct - All 6 versions

[PDF] Mitochondrial damages and the regulation of insulin secretion


P Maechler, PBM de Andrade - Biochemical Society Transactions, 2006 - maechler.unige.ch
Abstract Pancreatic β-cells are able to respond to nutrients, principally
glucose, as the primary stimulus for insulin exocytosis. This unique feature
requires translation of metabolic substrates into intracellular messengers ...
Cited by 13 - Related articles - View as HTML - BL Direct - All 7 versions

[beta]-Cell Function in Individuals Carrying the Mitochondrial tRNA Leu (UUR) Mutation


JE Salles, TS Kasamatsu, SA Dib, RS Moisés - Pancreas, 2007 - journals.lww.com
Skip Navigation Links Home > January 2007 - Volume 34 - Issue 1 > [beta]-Cell
Function in Individuals Carrying the Mitochondri... ... From the Division of
Endocrinology, Department of Medicine, Federal University of São Paulo, ...
Cited by 5 - Related articles - BL Direct - All 2 versions

m. 3243A> G Mutation in Mitochondrial DNA Leads to Decreased Insulin Sensitivity in …

- diabetesjournals.org
MM Lindroos, K Majamaa, A Tura, A Mari, KK … - Diabetes, 2009 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—We measured skeletal muscle glucose uptake and
perfusion using positron emission tomography and 2-[ 18 F]fluoro-2-deoxyglucose
and [ 15 O]H 2 O during euglycemic hyperinsulinemia in 15 patients with ...
Cited by 4 - Related articles - All 3 versions

High Prevalence of Impaired Glucose Homeostasis and Myopathy in Asymptomatic and …


AL Frederiksen, TD Jeppesen, J Vissing, M … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
Introduction: The point mutation of 3243A>G mtDNA is the most frequent cause of
mitochondrial diabetes, often presenting as the syndrome maternally inherited
diabetes and deafness (MIDD). The mutation may also cause myopathy, ataxia, ...
Related articles

[CITATION] Mitochondrial Diabetes: Clinical Specificity and Diagnosis


B VlALETTES, H NARBONNE - … Disorders: From Pathophysiology to Aquired Defects, 2002 - Springer France Editions
Related articles

Genetic influences on the insulin response of the beta cell to different secretagogues

- tweelingenregister.org [PDF] 
AMC Simonis-Bik, EMW Eekhoff, MHM de Moor, … - Diabetologia - Springer
Abstract Aims/hypothesis The aim of the present study was to estimate the
heritability of the beta cell insulin response to glucose and to glucose
combined with glucagon-like peptide-1 (GLP-1) or with GLP-1 plus arginine. ...
Related articles - All 3 versions


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