- ►diabetesjournals.org DJ Drucker - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic
peptide (GIP) exert important effects on β-cells to stimulate glucose-dependent
insulin secretion. Both peptides also regulate β-cell proliferation and ... Cited by 283 - Related articles - All 13 versions
- ►aspetjournals.org KE Mayo, LJ Miller, D Bataille, S Dalle, B … - Pharmacological reviews, 2003 - ASPET Peptide hormones within the secretin-glucagon family are expressed in endocrine
cells of the pancreas and gastrointestinal epithelium and in specialized neurons
in the brain, and subserve multiple biological functions, including ... Cited by 141 - Related articles - BL Direct - All 7 versions
DJ Drucker - eid, 2003 - informahealthcare.com Incretins are peptide hormones, exemplified by glucose-dependent insulino-
tropic peptide and glucagon-like peptide 1 that are released from the gut in
response to nutrient ingestion and enhance glucose-stimulated insulin ... Cited by 118 - Related articles - All 6 versions
- ►physiology.org JJ Holst - Physiological reviews, 2007 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in
the intestinal epithelial endocrine L-cells by differential processing of
proglucagon, the gene which is expressed in these cells. The current ... Cited by 113 - Related articles - BL Direct - All 5 versions
MK Lingohr, R Buettner, CJ Rhodes - Trends in molecular medicine, 2002 - Elsevier Obesity-linked type 2 diabetes is a disease of insulin resistance combined with
pancreatic β-cell dysfunction. Although a role for β-cell mass in the
pathogenesis of obesity-linked type 2 diabetes has recently gained ... Cited by 91 - Related articles - All 7 versions
- ►diabetesjournals.org B Laferrère, S Heshka, K Wang, Y Khan, J … - Diabetes Care, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Incretin (gastric inhibitory peptide [GIP] and
glucagon-like peptide-1 [GLP-1]) levels and their effect on insulin secretion
were measured before and 1 month after RY-GBP in eight obese women with ... Cited by 59 - Related articles - BL Direct - All 7 versions
PL Brubaker, Y Anini - Canadian journal of physiology and pharmacology, 2003 - article.pubs.nrc-cnrc.gc.ca Abstract: The proglucagon-derived peptide family consists of three highly
related peptides, glucagon and the glucagon-like peptides GLP-1 and GLP-2.
Although the biological activity of glucagon as a counter-regulatory ... Cited by 48 - Related articles - BL Direct - All 9 versions
- ►glucagon.com [PDF] T Hansotia, DJ Drucker - Regulatory peptides, 2005 - Elsevier Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1
(GLP-1) are gut-derived incretins secreted in response to nutrient ingestion.
Both incretins potentiate glucose-dependent insulin secretion and enhance ... Cited by 48 - Related articles - All 5 versions
B Ahrén - Expert Opin. Investig. Drugs, 2006 - informahealthcare.com Vildagliptin is a competitive and reversible inhibitor of dipeptidyl
peptidase-4. Dipeptidyl peptidase-4 inhibitors act mainly by preventing the
rapid degradation of glucagon-like peptide-1. In clinical trials, ... Cited by 43 - Related articles - BL Direct - All 6 versions
M Tadayyon, SA Smith - eid, 2003 - Informa Pharma Science Type 2 diabetes is reaching epidemic proportions worldwide, fuelled by the
increasing prevalence of obesity as many populations adopt a western life-
style. Secondary complications affecting both the microvascular and macrov- ... Cited by 27 - Related articles - All 4 versions
