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Scholar Results 1 - 10 of about 174 citing Kelley: Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treat.... (0.13 sec) 

Meta-analysis: pharmacologic treatment of obesity


Z Li, M Maglione, W Tu, W Mojica, D … - Annals of internal …, 2005 - Am Coll Physicians
Background: In response to the increase in obesity, pharmacologic treatments for weight loss
have become more numerous and more commonly used. ... Purpose: To assess the efficacy
and safety of weight loss medications approved by the US Food and Drug Administration ...
Cited by 327 - Related articles - BL Direct - All 8 versions

Long-term pharmacotherapy for overweight and obesity: a systematic review and …


R Padwal, SK Li, DCW Lau - International journal of obesity, 2003 - nature.com
CONTEXT: Safe and effective strategies to curb rising obesity prevalence rates are urgently needed
and medications may play a more prominent role in future therapeutic regimens. ...
OBJECTIVE: To review systematically the long-term efficacy and safety of approved ...
Cited by 317 - Related articles - BL Direct - All 10 versions

Clinical implications of obesity with specific focus on cardiovascular disease: a …

- ahajournals.org
S Klein, LE Burke, GA Bray, S Blair, DB Allison, X Pi- … - Circulation, 2004 - Am Heart Assoc
Obesity adversely affects cardiac function, increases the risk factors for coronary heart
disease, and is an independent risk factor for cardiovascular disease. The risk of developing
coronary heart disease is directly related to the concomitant burden of obesity-related risk ...
Cited by 279 - Related articles - BL Direct - All 8 versions

[PDF] Current and investigational antiobesity agents and obesity therapeutic treatment …


HE Bays - Obesity research, 2004 - toniyancey.com
Abstract BAYS, HAROLD E. Current and investigational antiobesity agents and obesity therapeutic
treatment targets. Obes Res. 2004;12:1197–1211. Public health efforts and current antiobesity
agents have not controlled the increasing epidemic of obesity. Investigational antiobesity ...
Cited by 127 - Related articles - View as HTML - BL Direct - All 9 versions

Effect of thiazolidinediones on body weight in patients with diabetes mellitus


V Fonseca - The American journal of medicine, 2003 - Elsevier
Treatment of diabetes mellitus with medications, including insulin, sulfonylureas, and thiazolidinediones
(TZDs), often leads to weight gain through a variety of mechanisms. Weight gain can have adverse
consequences for patients with type 2 diabetes, many of whom are overweight or obese, ...
Cited by 107 - Related articles - All 8 versions

Systematic review of long-term weight loss studies in obese adults: clinical …


JD Douketis, C Macie, L Thabane, DF … - International Journal of …, 2005 - nature.com
Dietary/lifestyle therapy provides <5 kg weight loss after 2–4 y, pharmacologic therapy provides
5–10 kg weight loss after 1–2 y, and surgical therapy provides 25–75 kg weight loss after 2–4
y. Weight loss of 5% baseline weight is not consistently associated with improvements in ...
Cited by 106 - Related articles - BL Direct - All 5 versions

Efficacy of pharmacotherapy for weight loss in adults with type 2 diabetes mellitus: …


SL Norris, X Zhang, A Avenell, E Gregg, CH … - Archives of internal …, 2004 - Am Med Assoc
Results Sufficient data for the meta-analysis were available for fluoxetine, orlistat, and
sibutramine. Fourteen randomized, placebo-controlled trials were included in the review, with
a total of 2231 patients. Pharmacotherapy produced modest reductions in weight for ...
Cited by 91 - Related articles - BL Direct - All 5 versions

Effects of moderate weight loss and orlistat on insulin resistance, regional adiposity …

- diabetesjournals.org
DE Kelley, LH Kuller, TM McKolanis, P Harper, J … - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS—Weight loss resulted in substantial improvement (P < 0.001) in HbA 1c (−1.6 ± 0.3
vs. −1.0 ± 0.4%; NS between groups). IS improved significantly more with orlistat (Δ2.2 ± 0.4
vs. Δ1.2 ± 0.4 mg · min −1 · kg −1 fat-free mass [FFM]; P < 0.05), and plasma free fatty acid ...
Cited by 86 - Related articles - BL Direct - All 12 versions

Oral antihyperglycemic therapy for type 2 diabetes mellitus

- ecmaj.ca
AYY Cheng, IG Fantus - Canadian Medical Association Journal, 2005 - ecmaj.ca
DIABETES MELLITUS IS A CHRONIC DISEASE that is growing in prevalence worldwide. Pharmacologic
therapy is often necessary to achieve optimal glycemic control in the management of
diabetes. Orally administered antihyperglycemic agents (OHAs) can be used either alone ...
Cited by 71 - Related articles - All 16 versions

What interventions should we add to weight reducing diets in adults with obesity? A …


A Avenell, TJ Brown, MA McGee, MK … - Journal of Human …, 2004 - interscience.wiley.com
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Cited by 67 - Related articles - BL Direct - All 7 versions


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