- ►jneurosci.org T Harada, C Harada, S Kohsaka, E Wada, K … - Journal of …, 2002 - Soc Neuroscience Activation of microglia commonly occurs in response to a wide variety of pathological stimuli
including trauma, axotomy, ischemia, and degeneration in the CNS. In the retina, prolonged
or high-intensity exposure to visible light leads to photoreceptor cell apoptosis. In such a ... Cited by 109 - Related articles - BL Direct - All 6 versions
C Harada, T Harada, HMA Quah, F Maekawa, K … - Neuroscience, 2003 - Elsevier Glial cell line-derived neurotrophic factor (GDNF), neurturin (NTN) and their receptors
(GFRα1, GFRα2 and Ret) play an important role in the survival of neurons in the central and
peripheral nervous system. For example, GDNF as well as other trophic factors promotes ... Cited by 31 - Related articles - All 5 versions
EJ Mayer, EH Hughes, DA Carter, AD Dick - British Journal of …, 2003 - bjo.bmj.com Results: Nestin positive cells are most prominent at the ora serrata, possess fibrillary
processes, small amounts of perinuclear cytoplasm, and are arranged radially within or superficially
on the retina. In the posterior retina, speckled cytoplasmic nestin staining is seen around ... Cited by 31 - Related articles - BL Direct - All 7 versions
C Harada, T Harada, Y Mitamura, HM Quah, K Ohtsuka … - Mol Vis, 2004 - molvis.org Purpose: Formation of epiretinal membranes (ERMs) after proliferative diabetic retinopathy
(PDR) and proliferative vitreoretinopathy (PVR) results in progressive deterioration of vision,
but its pathogenic mechanisms are still unknown. This study was conducted to examine ... Cited by 26 - Related articles - Cached - All 3 versions
- ►bentham.org [PDF] Y Mitamura, C Harada, T Harada - Current Diabetes Reviews, 2005 - ingentaconnect.com Abstract: Diabetic retinopathy (DR) is one of the most frequent complications of diabetes and
the leading cause of acquired blindness in developed countries. A note worthy problem in DR
is the formation of fibrovascular epiretinal membranes (ERMs) which can cause tractional ... Cited by 15 - Related articles - BL Direct - All 7 versions
C Harada, A Okumura, K Namekata, K Nakamura, … - Diabetes research and …, 2006 - Elsevier Intraocular concentrations of monocyte chemotactic protein-1 (MCP-1) are increased in proliferative
diabetic retinopathy (PDR). Nuclear factor kappa B (NF-κB) is a transcription factor, and NF-κB
binding site is located in gene promoter of MCP-1. This study was conducted to ... Cited by 14 - Related articles - All 10 versions
S Kase, W Saito, K Ohgami, K Yoshida, N … - British Journal of …, 2007 - bjo.bmj.com Results: The histopathological findings demonstrated that PDR membranes consisted of a variety
of endothelial cells forming a microvascular cavity with red blood cells and non-vascular stromal
mononuclear cells. Membranous and cytoplasmic immunoreactivity for EpoR was ... Cited by 16 - Related articles - BL Direct - All 3 versions
L Zhou, Y Wang, Y Zhang, Y Geng, L Si, Y Wang - Neuroscience Letters, 2006 - Elsevier Glioma is the most common malignant disease in the brain, and recurrence is the main cause
of death from this disease. Tumor recurrence involves multiple steps, and requires the accumulation
of the altered expression of many different proteins. Identification of the recurrence ... Cited by 9 - Related articles - All 2 versions
S Minchiotti, B Stampachiacchiere, A Micera, A … - Retina, 2008 - journals.lww.com Purpose: Glial cells and fibroblasts (FBs) play a key role in epiretinal membrane (ERM) development
and progression. Myofibroblasts (myoFBs), arising from these cells, can lead to the hypertrophic
scars and tissue contraction observed in ERMs. Nerve growth factor (NGF) and ... Cited by 2 - Related articles - BL Direct - All 3 versions