ML Caramori, M Mauer - Current opinion in nephrology and hypertension, 2003 - journals.lww.com Recent findings: There have been advances in the understanding of diabetic
nephropathy pathology. Clearly, structural changes may be advanced before any
clinical findings are apparent. Not all functional consequences of the ... Cited by 68 - Related articles - BL Direct - All 7 versions
G Wolf - Kidney international, 2006 - nature.com Glomerulosclerosis, interstitial fibrosis, and tubular atrophy occur with
end-stage kidney failure, irrespective of the primary etiology. The transforming
growth factor- (TGF- ) is a key factor in these alterations either ... Cited by 66 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org RE Gilbert, A Akdeniz, S Weitz, WR Usinger … - Diabetes Care, 2003 - Am Diabetes Assoc OBJECTIVE—Excretion of growth factors in the urine has been implicated in the
pathogenesis of tubulointerstitial disease that characterizes proteinuric renal
disease. In this cross-sectional study, we sought to examine the urinary ... Cited by 61 - Related articles - BL Direct - All 5 versions
- ►amjpathol.org CC Hou, W Wang, XR Huang, P Fu, TH Chen, … - American Journal of Pathology, 2005 - ASIP Transforming growth factor (TGF)-ß1 has been shown to play a critical role in
hypertensive nephropathy. We hypothesized that blocking TGF-ß1 signaling could
attenuate renal fibrosis in a rat model of remnant kidney disease. Groups ... Cited by 60 - Related articles - All 7 versions
RE Gilbert, H Krum, J Wilkinson-Berka, DJ … - Diabetic Medicine, 2003 - pt.wkhealth.com The relationship between the renin-angiotensin system (RAS) and the progression
of diabetic renal disease has been a major focus of investigation over the past
20 years. More recently, experimental and clinical studies have also ... Cited by 51 - Related articles - BL Direct - All 7 versions
PJ Lijnen, VV Petrov, RH Fagard - American Journal of Hypertension, 2003 - Elsevier Discordant findings are reported on the left ventricular transforming growth
factor-β 1 (TGF-β 1 ) mRNA levels in various rat models. Left ventricular
TGF-β 1 mRNA levels did not differ between spontaneously hypertensive rats ... Cited by 42 - Related articles - All 6 versions
- ►diabetesjournals.org [PDF] S Andersen, J Bröchner-Mortensen, HH … - Diabetes Care, 2004 - Am Diabetes Assoc Diabetic patients have been shown to excrete increased quantities of al- bumin,
which is undetectable by conventional albumin antibodies (immu- nounreactive)
using high-performance liq- uid chromatography (HPLC) (1). Furthermore, the ... Cited by 42 - Related articles - BL Direct - All 8 versions
UN Das - European journal of clinical nutrition, 2004 - nature.com Patients with uncontrolled essential hypertension have elevated concentrations
of superoxide anion (O 2 - ), hydrogen peroxide (H 2 O 2 ), lipid peroxides,
endothelin, and transforming growth factor- (TGF- ) with a simultaneous ... Cited by 35 - Related articles - BL Direct - All 7 versions
F SA, PR LT, LW KR, HP RG - Kidney international, 2005 - nature.com Seventy-one hypertensive type 1 diabetic patients with diabetic nephropathy were
included in the study. After a washout period of 4 weeks, the patients received
Losartan 50 mg, 100 mg, and 150 mg once daily in treatment periods each ... Cited by 34 - Related articles - All 3 versions
- ►perfline.com WT McBride, S Allen, SMC Gormley, IS Young … - Cytokine, 2004 - Elsevier Whilst elevated urinary transforming growth factor beta-1 (TGFβ) is associated
with chronic renal dysfunction its role in acute peri-operative renal
dysfunction is unknown. In contrast, peri-operative increases in urinary ... Cited by 30 - Related articles - All 5 versions