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Scholar Results 1 - 10 of about 20 citing Kotani: Detection of GAD65-reactive T-cells in type 1 diabetes by immunoglobulin-free ELISPOT assays. (0.11 sec) 

Defective suppressor function in CD4+ CD25+ T-cells from patients with type 1 diabetes


S Lindley, CM Dayan, A Bishop, BO Roep, M … - Diabetes, 2005 - Am Diabetes Assoc
Type 1 diabetes is a T-cell–mediated disease that is associated with loss of
immunological tolerance to self-antigens. The mechanisms involved in maintenance
of peripheral tolerance include a specialized subset of regulatory T-cells ...
Cited by 290 - Related articles - All 5 versions

Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive …


NC Schloot, G Meierhoff, M Karlsson Faresjö … - Journal of Autoimmunity, 2003 - Elsevier
The identification of sensitive assay formats capable of distinguishing islet
autoreactive T cells directly ex vivo in blood is a major goal in type 1
diabetes research. Recently, much interest has been shown in the cytokine ...
Cited by 43 - Related articles - All 4 versions

T lymphocyte response against pancreatic beta cell antigens in fulminant type 1 diabetes


R Kotani, M Nagata, A Imagawa, H Moriyama, … - Diabetologia, 2004 - Springer
Aims/hypothesis. Fulminant Type 1 diabetes is a novel subtype of Type 1 diabetes
that involves the abrupt onset of insulin-deficient hyperglycaemia. This sub-
type appears to be non-autoimmune because of the ab- sence of ...
Cited by 24 - Related articles - BL Direct - All 4 versions

[PDF] Detection of autoreactive T cells in type 1 diabetes using coded autoantigens and an …


M Nagata, R Kotani, H Moriyama, K Yokono, … - Ann. NY Acad. Sci, 2004 - cmbi.bjmu.cn
MASAO NAGATA,a REIKO KOTANI,a HIROAKI MORIYAMA,a KOICHI YOKONO,a BART O. ROEP,b
AND MARK PEAKMANc aDivision of Internal and Geriatric Medicine, Department of
Development and Aging, Kobe University Graduate School of Medicine, Kobe, ...
Cited by 12 - Related articles - View as HTML - All 8 versions

Th1 and Th2 cell responses of type 1 diabetes patients and healthy controls to human …


A Szebeni, N Schloot, V Kecskemeti, N … - Inflammation Research, 2005 - Springer
1 Department of Pharmacology and Pharmacotherapy, Semmelweis University, PO Box
370, 1445 Budapest, Hungary, Fax: ++ 00 361 210 4412, e-mail:
szeband@pharma.sote.hu 2 German Diabetes Clinic, German Diabetes Center, ...
Cited by 6 - Related articles - BL Direct - All 2 versions

Insulin as a T cell antigen in Type 1 diabetes supported by the evidence from the insulin …


H Moriyama, M Nagata, T Arai, Y Okumachi, … - Diabetes Research and Clinical Practice, 2007 - Elsevier
Rodents have two functional preproinsulin genes named insulin 1 and insulin 2 on
different chromosome and have two amino acid differences in insulin B chain. We
have established insulin 1 or insulin 2 knockout (KO) non-obese diabetic ...
Cited by 4 - Related articles - All 9 versions

Immunological aspects of 'fulminant type 1 diabetes'


M Nagata, H Moriyama, R Kotani, H Yasuda, M … - Diabetes Research and Clinical Practice, 2007 - Elsevier
'Fulminant diabetes' has been recognized as a super-acute onset and
non-autoimmune type 1 diabetes. To evaluate autoimmunity against pancreatic β
cell in fulminant diabetes, ELISPOT assay was applied to the peripheral ...
Cited by 4 - Related articles - All 7 versions

Anti-GAD65 reactive peripheral blood mononuclear cells in the pathogenesis of cystic …


K Stechova, S Kolouskova, Z Sumnik, O Cinek … - Autoimmunity, 2005 - informahealthcare.com
Objective: A role of autoreactive T cells for type 1 diabetes pathogenesis is
considered crucial. In our pilot study we addressed if autoreactive mononuclear
cells are present also in peripheral blood of patients with other specific ...
Cited by 5 - Related articles - All 8 versions

LADA 的诊断要点与治疗方式


周智广, 杨琳 - 中华内分泌代谢杂志, 2006 - cqvip.com
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Cited by 4 - Related articles - All 3 versions

GAD65 autoimmunity—clinical studies


R Uibo, A Lernmark - Immunopathogenesis of Type 1 Diabetes Mellitus, 2008 - books.google.com
GAD65 Autoimmunity—Clinical Studies O j. Raivo Uibo* and Ake Lernmark Contents
1. Introduction 40 1.1. From 64K to GAD65 (1981-1991) 41 1.2. GAD65 and GAD67
structure and function 43 2. GAD65 Autoimmunity in T1D 48 2.1. Cellular ...
Cited by 2 - Related articles - All 2 versions


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