JD Browning, LS Szczepaniak, R Dobbins, P … - Hepatology, 2004 - interscience.wiley.com Despite the increasing prevalence of nonalcoholic fatty liver disease (NAFLD), its pathogenesis
and clinical significance remain poorly defined. In this study, we examined and compared the
distribution of hepatic triglyceride content (HTGC) in 2,287 subjects from a multiethnic, ... Cited by 532 - Related articles - All 3 versions
PJ Havel - Diabetes, 2004 - Am Diabetes Assoc Hormones produced by adipose tissue play a critical role in the regulation of energy intake, energy
expenditure, and lipid and carbohydrate metabolism. This review will address the biology,
actions, and regulation of three adipocyte hormones—leptin, acylation stimulating protein ... Cited by 341 - Related articles - BL Direct - All 7 versions
- ►shouxi.net A Garg - The New England journal of medicine, 2004 - nejm.org Lipodystrophies are clinically heterogeneous acquired or inherited disorders characterized by
the selective loss of adipose tissue. Affected patients are predisposed to insulin resistance and
its attendant complications, including diabetes mellitus, dyslipidemia, hepatic steatosis, ... Cited by 251 - Related articles - BL Direct - All 10 versions
- ►physiology.org LS Szczepaniak, P Nurenberg, D Leonard … - American Journal of …, 2005 - Am Physiological Soc Despite the increasing prevalence of nonalcoholic fatty liver disease (NAFLD), the criteria used
to diagnose the disorder remain poorly defined. Localized proton magnetic resonance spectroscopy
(MRS) accurately measures hepatic triglyceride content (HTGC) but has been used only ... Cited by 234 - Related articles - All 4 versions
LK Heilbronn, E Ravussin - American Journal of Clinical Nutrition, 2003 - Am Soc Nutrition Calorie restriction (CR) extends life span and retards age-related chronic diseases in a variety
of species, including rats, mice, fish, flies, worms, and yeast. The mechanism or mechanisms
through which this occurs are unclear. CR reduces metabolic rate and oxidative stress, ... Cited by 189 - Related articles - BL Direct - All 9 versions
PJ Havel - Nutrition reviews, 2005 - ingentaconnect.com Fructose intake and the prevalence of obesity have both increased over the past two to three
decades. Compared with glucose, the hepatic metabolism of fructose favors lipogenesis, which
may contribute to hyperlipidemia and obesity. Fructose does not in- crease insulin and ... Cited by 127 - Related articles - All 8 versions
- ►bmj.com EL Thomas, G Hamilton, N Patel, R O'dwyer, CJ … - British Medical …, 2005 - gut.bmj.com Results: IHCL signals were detectable in all subjects but were significantly greater in hepatic
steatosis (geometric mean (GM) 11.5 (interquartile range (IQR) 7.0–39.0)) than in normal volunteers
(GM 2.7 (IQR 0.7–9.3); p = 0.02). In the study group as a whole, IHCL levels were ... Cited by 113 - Related articles - BL Direct - All 16 versions
M Faraj, HL Lu, K Cianflone - Biochemistry and Cell Biology, 2004 - article.pubs.nrc-cnrc.gc.ca Abstract: That obesity is associated with insulin resistance and type II diabetes mellitus is well
accepted. Overloading of white adipose tissue beyond its storage capacity leads to lipid disorders
in non-adipose tissues, namely skeletal and cardiac muscles, pancreas, and liver, effects ... Cited by 78 - Related articles - BL Direct - All 7 versions
M Roden - Nature Reviews Endocrinology, 2006 - nature.com Hepatic steatosis is defined by an increased content of hepatocellular lipids (HCLs) and is frequently
observed in insulin-resistant states including type 2 diabetes mellitus. A dietary excess of saturated
fat contributes significantly to HCL accumulation. Elevated HCL levels mainly account for ... Cited by 73 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Garg, A Misra - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc For a long time, fatty liver or hepatic steatosis was considered as a benign manifestation.
However, recent data indicate a wide spectrum of clinical and pathological manifestations that
subjects with nonalcoholic hepatic steatosis develop, which are termed as nonalcoholic ... Cited by 73 - Related articles - BL Direct - All 4 versions
