- ►physiology.org JJ Holst, J Gromada - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc The available evidence suggests that about two-thirds of the insulin response to
an oral glucose load is due to the potentiating effect of gut-derived incretin
hormones. The strongest candidates for the incretin effect are ... Cited by 180 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org KB Degn, CB Juhl, J Sturis, G Jakobsen, B … - Diabetes, 2004 - Am Diabetes Assoc Glucagon-like peptide 1 (GLP-1) is potentially a very attractive agent for
treating type 2 diabetes. We explored the effect of short-term (1 week)
treatment with a GLP-1 derivative, liraglutide (NN2211), on 24-h dynamics ... Cited by 168 - Related articles - BL Direct - All 8 versions
- ►physiology.org JJ Holst - Physiological reviews, 2007 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in
the intestinal epithelial endocrine L-cells by differential processing of
proglucagon, the gene which is expressed in these cells. The current ... Cited by 113 - Related articles - BL Direct - All 5 versions
GS Meneilly - Medical Clinics of North America, 2006 - Elsevier Numerous studies over the last decade have evaluated the incidence and
prevalence of diabetes in the elderly. Although differing diagnostic criteria
have been used, these studies consistently found an increased prevalence of ... Cited by 76 - Related articles - BL Direct - All 7 versions
- ►glucagon.com [PDF] - Free from Publisher MC Riddle, DJ Drucker - Diabetes Care, 2006 - Am Diabetes Assoc Current therapies for type 2 diabetes are frequently associated with inadequate
control of postprandial hyperglycemia, weight gain, and, in the case of oral
agents, loss of efficacy over time. A better understanding of physiological ... Cited by 71 - Related articles - BL Direct - All 10 versions
BE Dunning, JE Foley, B Ahren - Diabetologia, 2005 - Springer Abstract Although there is abundant evidence that hyper- glucagonaemia plays a
key role in the development of hy- perglycaemia in type 2 diabetes, efforts to
understand and correct this abnormality have been overshadowed by the ... Cited by 70 - Related articles - BL Direct - All 3 versions
- ►shouxi.net S Park, X Dong, TL Fisher, S Dunn, AK Omer, … - Journal of Biological Chemistry, 2006 - ASBMB The insulin receptor substrate 2 (Irs2) branch of the insulin/insulin-like
growth factor-signaling cascade prevents diabetes in mice because it promotes β
cell replication, function, and survival, especially during metabolic ... Cited by 65 - Related articles - BL Direct - All 8 versions
GG Sokos, LA Nikolaidis, S Mankad, D Elahi … - Journal of cardiac failure, 2006 - Elsevier We investigated the safety and efficacy of a 5-week infusion of GLP-1 (2.5
pmol/kg/min) added to standard therapy in 12 patients with New York Heart
Association class III/IV heart failure and compared the results with those ... Cited by 62 - Related articles - All 12 versions
DJ Drucker - Nature Clinical Practice Endocrinology and Metabolism, 2005 - glucagon.com INTRODUCTION Before the cDNAs and genes encoding pro glucagon were cloned,
pancreatic glucagon was the prin- cipal proglucagon-derived peptide (PGDP) with
well-characterized biologic actions. However, antisera directed against ... Cited by 59 - Related articles - View as HTML - BL Direct - All 6 versions
