- Free from Publisher B Ahrén, R Gomis, E Standl, D Mills, A … - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—In patients randomized to LAF237, baseline HbA 1c averaged 7.7 ± 0.1%
and decreased at week 12 (Δ = −0.6 ± 0.1%), whereas HbA 1c did not change
from a baseline of 7.9 ± 0.1% in patients given placebo (between-group ... Cited by 310 - Related articles - BL Direct - All 8 versions
- ►endojournals.org A Mari, WM Sallas, YL He, C Watson, M … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Results: Vildagliptin significantly increased the insulin secretory rate at 7
mmol/liter glucose (secretory tone), calculated from the dose response; the
difference in least squares mean ( LSM) was 101 ± 51 pmol·min –1 ·m ... Cited by 193 - Related articles - BL Direct - All 8 versions
BE Dunning, JE Foley, B Ahren - Diabetologia, 2005 - Springer Abstract Although there is abundant evidence that hyper- glucagonaemia plays a
key role in the development of hy- perglycaemia in type 2 diabetes, efforts to
understand and correct this abnormality have been overshadowed by the ... Cited by 70 - Related articles - BL Direct - All 3 versions
A Barnett - International journal of clinical practice, 2006 - nerdoc.wordpress.com The dipeptidyl peptidase 4 (DPP-4) inhibitors enhance the body's own ability to
control blood glucose by increas- ing the active levels of incretin hormones in
the body. Their mechanism of action is distinct from any existing class of ... Cited by 69 - Related articles - View as HTML - BL Direct - All 7 versions
- ►physiology.org A Gastaldelli, E Ferrannini, Y Miyazaki, M … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Thiazolidinediones (TZDs) improve glycemic control and insulin sensitivity in
patients with type 2 diabetes mellitus (T2DM). There is growing evidence from in
vivo and in vitro studies that TZDs improve pancreatic -cell function. The ... Cited by 39 - Related articles - BL Direct - All 6 versions
GM Steil, C Hwu, R Janowski, F Hariri, S … - Diabetes, 2004 - Am Diabetes Assoc Modeling analysis of glucose, insulin, and C-peptide following a meal has been
proposed as a means to estimate insulin sensitivity (S i ) and β-cell function
from a single test. We compared the model-derived meal indexes with ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►physiology.org E Muscelli, A Mari, A Natali, BD Astiarraga, S … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc The mechanisms by which the enteroinsular axis influences -cell function have
not been investigated in detail. We performed oral and isoglycemic intravenous
(IV) glucose administration in subjects with normal (NGT; n = 11) or ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Mari, WA Scherbaum, PM Nilsson, G Lalanne … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Design: A 52-wk double-blind, randomized, parallel-group study comparing
vildagliptin (50 mg every day) and placebo was conducted in 306 patients with
mild hyperglycemia (glycosylated hemoglobin of 6.2–7.5%). Plasma glucose ... Cited by 19 - Related articles - BL Direct - All 4 versions
A Mari, LL Nielsen, N Nanayakkara, RA … - Hormone and metabolic research, 2006 - cat.inist.fr The incretin mimetic exenatide improved glycemic control and reduced body weight
in patients with type 2 diabetes inadequately controlled with metformin ± a
sulfonylurea. We assessed postprandial β-cell function by mathematical ... Cited by 18 - Related articles - BL Direct - All 3 versions
