MY Donath, PA Halban - Diabetologia, 2004 - Springer Increasing evidence indicates that decreased functional beta-cell mass is the hallmark of both
Type 1 and Type 2 diabetes. This underlies the absolute or relative insu- lin insufficiency in both
conditions. In this For Debate, we consider the possible mechanisms responsible for beta- ... Cited by 123 - Related articles - BL Direct - All 6 versions
- ►endojournals.org BM Brooks-Worrell, CJ Greenbaum, JP Palmer, … - Journal of Clinical …, 2004 - Endocrine Soc Autoantibody and T cells reacting with islet proteins have been demonstrated in patients with
type 1 diabetes. In recent years an increasing number of children have been clinically classified
with type 2 (not ketosis prone, evidence of insulin resistance, presence of acanthosis ... Cited by 46 - Related articles - BL Direct - All 5 versions
- ►fetalneonatal.com … , E Schober, S Wiegand, A Thon … - … of disease in …, 2006 - adc.bmjjournals.com.p.angrylapdog. … Results: A total of 6922 children were clinically classified as having type 1 diabetes (T1DM) and
128 children as having T2DM. Thirty six per cent of the children with T2DM had at least one detectable
ß-cell autoantibody. These children did not differ significantly from the children with T2DM ... Cited by 45 - Related articles - BL Direct - All 11 versions
N Gungor, T Hannon, I Libman, F Bacha, S … - The Pediatric Clinics of …, 2005 - Elsevier Type 2 diabetes mellitus (T2DM) historically was considered a disease of adults, with autoimmune
type 1 diabetes mellitus (T1DM) accounting for almost all cases of pediatric diabetes. T2DM was
recognized as a disease of the pediatric age group by the late 1970s. It has turned into a ... Cited by 44 - Related articles - All 16 versions
- ►shouxi.net T Quattrin, E Liu, N Shaw, B Shine, E Chiang - Pediatrics, 2005 - Am Acad Pediatrics Results. The database included 587 children (mean age at referral: 9.5 years) with a preponderance
of non-Hispanic white children (75.6%) and female gender (57.6%). Growth records in 251 children
indicated that 80.6% of the children had become obese before the age of 6 years and ... Cited by 42 - Related articles - All 7 versions
EAM Gale - Diabetologia, 2005 - Springer Childhood diabetes appears to have been a relatively rare disorder in Europe and North America
in the first half of the 20th century, with incidence rates comparable to those seen in some Asian
populations today. The incidence began to rise around the middle of the twentieth ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►shouxi.net R Alemzadeh, T Berhe, DT Wyatt - Pediatrics, 2005 - Am Acad Pediatrics Background and Objectives. Insulin replacement regimens now stress the importance of administering
throughout the day insulin doses that are based on flexible food choices and focusing on improved
metabolic control. A flexible multiple daily insulin (FMDI) regimen (premeal lispro plus ... Cited by 38 - Related articles - All 8 versions
- ►diabetesjournals.org NA Sherry, EB Tsai, KC Herold - Diabetes, 2005 - Am Diabetes Assoc Despite extensive and ongoing investigations of the immune mechanisms of autoimmune diabetes
in humans and animal models, there is much less information about the natural history of insulin
secretion before and after the clinical presentation of type 1 diabetes and the factors that ... Cited by 37 - Related articles - BL Direct - All 6 versions
D Botero, JI Wolfsdorf - Archives of medical research, 2005 - Elsevier Until recently, diabetes in children was virtually synonymous with type 1 diabetes mellitus, whereas
type 2 diabetes was a disease of middle age and the elderly. Over the past 10–20 years, an alarming
increase in the prevalence of type 2 diabetes has been reported from pediatric diabetes ... Cited by 28 - Related articles - All 13 versions
AL Rosenbloom - Diabetes Care, 2003 - Am Diabetes Assoc Challenges to the concept of two main and distinct forms of diabetes go back to epidemiologic
studies in the 1960s and 1970s. Yemenite immigrants to Israel had very few instances of diabetes
but, after 25 years in the land of milk and honey, experienced a 40-fold increase in ... Cited by 28 - Related articles - BL Direct - All 5 versions
